1.6 Muscle Physiology

Question 1

determines the number of actin sites available for cross-bridge binding

Answer 1

Calcium

Question 2

Extends along the length of the thin filament; aligns the actin

Answer 2

Nebulin

Question 3

Largest known protein; participate in the formation of a scaffold for organization and lighnment of thick filaments

Answer 3

Titin

Question 4

Stabilizes the sarcolemma and prevents contraction-induced injury (rupture)

Answer 4

Dystrophin-glycoprotein complex

Question 5

Where calcium binds to cause the conformational change that exposes actin-myosin binding sites

Answer 5

Torponin C

Question 6

Conformational change of this receptor after the propagation of action potential in the T tubule opens calcium release channels in the SR

Answer 6

Dihydropyridine receptor (DHP)

Question 7

Slips into the groove of the actin filament and exposes myosin-binding sites on the actin filament after binding of calcium to troponin C

Answer 7

Tropomyosin

Question 8

Helps accumulate Ca2+ in the terminal cisternae

Answer 8

Calsequestrin

Question 9

This action allows the myosin to detach from actin

Answer 9

Binding of ATP to myosin

Question 10

Resting membrane potential of muscle is

Answer 10

-90 mV