1.4 Synaptic Physiology

Question 1

Point of communication between 2 neurons or a neuron and an effector organ

Answer 1

Synapse

Question 2

Short process emanating from the soma

Answer 2

Dendrites

Question 3

Long process emanating from the soma

Answer 3

Axon

Question 4

Terminal portion of an axon where mitochondria and RER are typically found

Answer 4

Presynaptic neuron

Question 5

Neurotoxin that targets synaptobrevin to block the fusion of synaptic vesicles

Answer 5

TetanusBotulium B,D,F,G

Question 6

Neurotoxin that targets SNAP-25 to block the fusion of synaptic vesicles

Answer 6

Botulinum A/E

Question 7

Neurotoxin that targets Syntaxin to block the fusion of synaptic vesicles

Answer 7

Botulinum C1

Question 8

Temporary depolarization of postsynaptic membrane cause by the flow of positively charged ions into the postsynatic cell

Answer 8

Excitatory Postsynaptioc Potential (EPSP)

Question 9

Temporary hyperpolarization of postsynaptic membrane caused by the flow of negatively charged ions into the postsynaptic cell

Answer 9

Inhibitory Postsynaptic Potential (IPSP)

Question 10

Postsynaptic potentials of 2 or more neurons combined at the same time (type of summation)

Answer 10

Spatial summation

Question 11

When a cell receives input that are close in time, they are also added together (type of summation)

Answer 11

Temporal summation

Question 12

Pharmacologic agents and toxins that affect NMJ:Blocks the binding of Ach with receptors

Answer 12

CurareAlpha bugarotoxin

Question 13

Pharmacologic agents and toxins that affect NMJ:Inhibits the release of Ach

Answer 13

Botulinum toxin

Question 14

Pharmacologic agents and toxins that affect NMJ:Clumps the Ach vesicles causing the massive release of Ach

Answer 14

Black widow spider toxin

Question 15

Pharmacologic agents and toxins that affect NMJ:Irreversible inactivation of Ach

Answer 15

Organophosphates