43. NUCLEAR MEDICINE: BETA PLUS DECAY Flashcards

1
Q
  1. What is Beta Plus (β+) Decay characterised by?
A
  • the production of positrons
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2
Q
  1. What are Positron Emitters?
A
  • they are the Radionuclides that undergo Beta Plus
    Decay
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3
Q
  1. In which situations do we use Positron Emitters?
A

WE USE THEM IN MEDICINE FOR:
- functional imaging
- with Positron Emission Tomography (PET)

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4
Q
  1. Name one example of Beta Plus Decay?
A
  • the decay of Nitrogen 13
  • into Carbon 13

CARBON 13 HAS A HALF LIFE OF:
- 10 minutes

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5
Q
  1. Does this image make sense?
A
  • yes
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6
Q
  1. What is Nitrogen-13?
A
  • this is a proton rich Radionuclide
  • it is produced in a Cyclotron
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7
Q
  1. How is Nitrogen-13 (labelled as Ammonia) inserted into the patient’s body?
A
  • it is injected intravenously into the body
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8
Q
  1. What is Nitrogen-13 (labelled as Ammonia) used for in medicine?
A
  1. CARDIAC IMAGING
    - for diagnosis of Coronary Artery Disease
    - diagnosis of Myocardial Infraction
  2. LIVER IMAGING
  3. BRAIN IMAGING
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9
Q
  1. What happens when Fluorine-18 undergoes Beta decay?
A
  • it decays into Oxygen-18
  • this has a half life of 110 minutes
  • this is a very important practical example
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10
Q
  1. What is Fluorodeoxyglucose (FDG)?
A
  • this a kind of Radionuclide of Fluorine-18
  • it is a sugar compound
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11
Q
  1. What do we use FDG (labelled as Fluorine-18) for?
A
  • we use it in PET functional imaging
  • it is injected intravenously into a patient
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12
Q
  1. What helps the FDG PET scan to detect abnormalities in the body?
A
  • increased glucose metabolism
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13
Q
  1. What can FDG PET scans detect?
A
  1. Malignant Diseases
  2. Distinguish Benign from Malignant Diseases
  3. Staging of Malignant Diseases
  4. Monitoring the response to therapy of Malignant
    Diseases
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