38. regressive changes in the heart muscle and their pathological appearance. Myocarditis Flashcards
regressive changes in heart muscle
hydropic degeneration
fatty infiltration
fatty degeneration
lipofuscinosis
myofibrillar degeneration
mineralization
myocardial necrosis
cause of myocardial necrosis
nutritional deficiencies
toxicities
physical injuries and shock
infections
myocardial infarct
toxicities causing myocardial necrosis
ionpohores
vit d
calcinogenic
t2 mycotoxin
uraemia
myocardial necrosis
focal, multifocal, diffuse
pale, dry
+/- gritty
outcome is either acute or chronic cardiac failure
healing of myocardial necrosis
by fibrosis
hydropic degeneration
due to
antineoplastic drugs
antiretroviral drugs
autointoxication
fatty infiltration
between the cardiac muscle fibres
fatty degeneration
in the sarcoplasma
due to anaemia and toxemia
lipofuscinosis
brown atrophy, accumulation of debris
due to ageing and cachexia
myofibrillar degeneration
aka myocytolysis
furazolidon toxicity in plants
mineralization
due to
vit e deficiency
vit d toxicity
calcinogenic plants
myocarditis cause
infections spread hematogenously to the myocardium
inflammation can spread from endo/peri cardium
lesions of myocarditis
pale areads
abscess or phlegmone in suppurative myocarditis
Outcome of myocarditis
complete resolution
residual scars
progressive myocardial damage
viral diseases causing myocarditis
parvo
pseudorabies
FMDV
encephalomyocarditis
distemper
bacteria diseases causing myocarditis
cl. chauvoei
listeria monocytogenes
cl. piliforme
fusobacterium necrophorum
mycobacterium
strep
actinobacillus equuli
steph
pastuerlla multocida
protozoa diseases causing myocarditis
toxoplasma
sarcocystic
encephalitozooon cuniculi
trypanosoma cruzi
paratitic diseases causing myocarditis
cysticercus cellulosae
trichinella spiralis
idiopathic diseases causing myocarditis
eosinophilic myocarditis
forms of myocarditis
serous myocarditis
lymphoplasmacytic/ lymphohistiocytic
purulent
putrid
eosinophilic
necrotizing
chronic
serous myocarditis
inflammatory oedema
compression of myoctes
wavy appearance
complete resolution is possible
lymphoplasmacytic
most frequent
caused my viruses
regressive alteration of myocytes
lymphocytes, plasma cells, histiocytes
purulent myocarditis
pyogenic bacteria
by metastasis originating from vegetative valvular endocarditis on AV valves
or direct contact
lesions of purulent myocarditis
septic infarcts
abscess formation
disseminated lesions
neutrophils and necrotic debris
phlegmone
