22. Enterotoxemias caused by Clostridium perfringens Flashcards

1
Q

number of cl. perfringens

A

5
a, b, c, d, e

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2
Q

predisposition to cl. perfringens

A

decreased gut motility
overeating with carb rich food
imbalance of microbial flora of the gut

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3
Q

toxin of cl. perfringens A

A

alpha

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4
Q

toxin of cl. perfringens B

A

alpha
beta
epsilon

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5
Q

toxin of cl. perfringens C

A

alpha
beta

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6
Q

toxin of cl. perfringens D

A

alpha
epsilon

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7
Q

toxin of cl. perfringens E

A

alpha
I

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8
Q

diseases of cl. perfringens A

A

human gas gangrene
food poisoning
necrotic enteritis of chicken
haemorrhagic necrotic enteritis

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9
Q

diseases of cl. perfringens B

A

lamb dystentry

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10
Q

disease of cl. perfringens c

A

struck
necrotic enteritis of piglets and chicken

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11
Q

diseases of cl. perfringens d

A

enterotoxaemia of sheep and goat

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12
Q

diseases of cl. perfringens e

A

necrotic typhlitis of rabbit
haemorrhagic enteritis of calves

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13
Q

clinical signs of cl. perfringens

A

sudden death
watery, bloody diarrhoea
glucosuria in lambs

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14
Q

lesions of cl. perfringens

A

focal/diffuse congestion of small intestines
petechiae
coagulation necrosis of mucosa
degeneration of other organs

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15
Q

cl. perfringens in pig

A

haemorrhagic/necrotic enteritis

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16
Q

cl. perfringens in sheep

A

overeating disease
pulpy kidney
lamb dystentry

17
Q

cl. perfringens in birds

A

necrotic and ulcerative enterittis

18
Q

cl. perfringens in dog

A

acute haemorrhagic gastro enteritis

19
Q

infection of lamb dysentry

A

suckling from contaminated mammary gland

20
Q

pathology of lamb dysentry

A

myocardial degeneration

21
Q

pathology of struck

A

reddish fluid in abdo cavity
haemorrhage & fibrin covered ulcers in small intestine
bleeding under serous membranes

22
Q

age of affected piglets in necrotizing enteritis

23
Q

toxins of necrotizing enteritis

A

alpha
beta

24
Q

localisation of necrotizing enteritis in piglets

A

middle jejunum

25
peracute necrotizing enteritis
severe haemorrhagic enteritis foamy intesting content
26
subacute necrotizing enteritis
necrosis of mm intestinal wall becomes rigid tube like longitudinal/ transverse mm folding
27
pathogenesis of cl. perfringens D
hypomotility and overgrowth produce epsilon toxin increase intestinal permeability damaging parenchymal organs endothelial injury in brain tubulonephrosis glucouria
28
lethal effects of the toxin of cl. perfringens
myocardial damage, coagulating serum in pericardium bleeding under epicardium focal symmetrical ecephalomalacia sudden kidney autolysis
29
lesions of cl. perfringens
exsiccosis spf necrotising/colitits
30
clinical signs of cl. perfringens
pasty then watery diarrhoea emaciation exsiccosis varying morbidity & mortality
31
clinical signs of cl. difficile
diarrhoea laboured breathing sudden death scrotal oedema
32
pathology of cl. difficile
mesocolon oedema necrotic colitis ascites small intestine not affected