22. Enterotoxemias caused by Clostridium perfringens Flashcards

1
Q

number of cl. perfringens

A

5
a, b, c, d, e

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2
Q

predisposition to cl. perfringens

A

decreased gut motility
overeating with carb rich food
imbalance of microbial flora of the gut

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3
Q

toxin of cl. perfringens A

A

alpha

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4
Q

toxin of cl. perfringens B

A

alpha
beta
epsilon

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5
Q

toxin of cl. perfringens C

A

alpha
beta

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6
Q

toxin of cl. perfringens D

A

alpha
epsilon

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7
Q

toxin of cl. perfringens E

A

alpha
I

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8
Q

diseases of cl. perfringens A

A

human gas gangrene
food poisoning
necrotic enteritis of chicken
haemorrhagic necrotic enteritis

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9
Q

diseases of cl. perfringens B

A

lamb dystentry

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10
Q

disease of cl. perfringens c

A

struck
necrotic enteritis of piglets and chicken

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11
Q

diseases of cl. perfringens d

A

enterotoxaemia of sheep and goat

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12
Q

diseases of cl. perfringens e

A

necrotic typhlitis of rabbit
haemorrhagic enteritis of calves

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13
Q

clinical signs of cl. perfringens

A

sudden death
watery, bloody diarrhoea
glucosuria in lambs

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14
Q

lesions of cl. perfringens

A

focal/diffuse congestion of small intestines
petechiae
coagulation necrosis of mucosa
degeneration of other organs

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15
Q

cl. perfringens in pig

A

haemorrhagic/necrotic enteritis

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16
Q

cl. perfringens in sheep

A

overeating disease
pulpy kidney
lamb dystentry

17
Q

cl. perfringens in birds

A

necrotic and ulcerative enterittis

18
Q

cl. perfringens in dog

A

acute haemorrhagic gastro enteritis

19
Q

infection of lamb dysentry

A

suckling from contaminated mammary gland

20
Q

pathology of lamb dysentry

A

myocardial degeneration

21
Q

pathology of struck

A

reddish fluid in abdo cavity
haemorrhage & fibrin covered ulcers in small intestine
bleeding under serous membranes

22
Q

age of affected piglets in necrotizing enteritis

A

1-2week

23
Q

toxins of necrotizing enteritis

A

alpha
beta

24
Q

localisation of necrotizing enteritis in piglets

A

middle jejunum

25
Q

peracute necrotizing enteritis

A

severe haemorrhagic enteritis
foamy intesting content

26
Q

subacute necrotizing enteritis

A

necrosis of mm
intestinal wall becomes rigid tube like
longitudinal/ transverse mm folding

27
Q

pathogenesis of cl. perfringens D

A

hypomotility and overgrowth
produce epsilon toxin
increase intestinal permeability
damaging parenchymal organs
endothelial injury in brain
tubulonephrosis
glucouria

28
Q

lethal effects of the toxin of cl. perfringens

A

myocardial damage, coagulating serum in pericardium
bleeding under epicardium
focal symmetrical ecephalomalacia
sudden kidney autolysis

29
Q

lesions of cl. perfringens

A

exsiccosis
spf necrotising/colitits

30
Q

clinical signs of cl. perfringens

A

pasty then watery diarrhoea
emaciation
exsiccosis
varying morbidity & mortality

31
Q

clinical signs of cl. difficile

A

diarrhoea
laboured breathing
sudden death
scrotal oedema

32
Q

pathology of cl. difficile

A

mesocolon oedema
necrotic colitis
ascites
small intestine not affected