3.6 Epigenetics 2 Flashcards
What is Genomic imprinting
certain genes are expressed in a parent of origin specific manner.
How is GI associated with diseases like Prader-Willi syndrome
The child inherited two copies of chromosome 15 from the mother and no chromosome 15 from the father
What is uniparental disomy
inheriting 2 copies of a chromosome from one parent
What are two diseases caused by uniparental disomy?
PWS and AS
What is an ex of environmental influence of the epigenome and its consequence?
Diet can effect methylation patterns in genome
What is the significance of epigenetic biomarkers for health outcomes prediction and what would insurance companies do with this info
Can catch diseases before they progress and can possible cure them. Insurance companies are going to use this info against potential customers and not give them insurance.
How is the agouti mouse used as a biosensor for environmental modifiers of the epigenome
The mouses coat and weight gain indicates increased levels of lead exposure
What environmental contributors to the epigenome play a role in cancer?
smoking, weight gain,
