3.4. Glándula paratiroides Flashcards

1
Q

Hormonas qué regulan el Ca2+

A

Calcitonina y PTH → Incrementan
Calcitonina → Disminuye

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1
Q

Tipos de Ca2+

A

Difusible → Involucrado en procesos celulares
No difusible → Unido a albumina

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2
Q

Hormona que regula el Ca2+ en sangre

A

PTH

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3
Q

Niveles de Ca2+ en sangre

A

8.5-10

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4
Q

Dónde actúa la vitamina D activa

A

Enterocitos → Calcitriol

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5
Q

Función de la vitamina D

A

Absorción de Ca2+ de la comida

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6
Q

Células qué producen la PTH

A

Principales

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7
Q

Células qué componen la glándula paratiroides

A
  • Principales
  • Oxifilicas
  • Acuosas
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8
Q

Efectos de la hipercalcemia

A
  • Depresión del SN
  • Acortamiento del intervalo QT
  • Esterñimiento
  • Pérdida de peso
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9
Q

Efectos de la hipocalcemia

A

Excitación del SN

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10
Q

Efecto de la disminución de Ca2+ en los riñones

A

Reasorción → Aumento sérico

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11
Q

Efectos de la disminución Ca2+ en los huesos

A

Rutura de cristales CaPO → Aumento sérico.
Osteoblastos → RANKL, M-CSF y OPG.

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12
Q

¿Quién secreta a la calcitonina?

A

Células parafoliculares

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13
Q

Función de la calcitonina

A

Reduce Ca2+ sérico
Inhibe PTH

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14
Q

Molécula que estimula la reasorción

A

1,25-dihidroxivitamina D

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15
Q

Gen que trancribe a la 1-alfa-hidroxilasa

A

CYP27B1

16
Q

Función 1 alfa-hidroxilasa

A

D3 → calcitriol

17
Q

Molécula a la que se une el Ca2+ en los enterocitos

A

Calbindina