3.3. Función tiroidea Flashcards

1
Q

Hormonas que secreta

A
  • T3
  • T4
  • Calcitonina
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2
Q

¿Qué ocurre con mayor frecuencia, una deficiencia o una sobreproducción?

A

Sobre producción

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3
Q

Características de la T3

A

Menor cantidad
Mayor potencia

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4
Q

Características de la T4

A

Mayor cantidad
Menor potencia

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5
Q

Conversión en tejidos

A

T4 → T3

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6
Q

Forma activa de las hormonas tiroideas

A

Libres en sangre → 0.03%

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7
Q

Forma inactiva de las hormonas tiroideas

A

Unidas a la globulina fijadora a la tiroxina, prealbumina, albumina fijadora de tiroxina.

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8
Q

Enzima que convierte t4 → t3

A

5-deiodinasa

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9
Q

Hormona tiroidea que activa la transcripción de gene

A

T3

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10
Q

Organificación de la tiroglobulina

A

Unión de I a tiroglobulina

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11
Q

Tiocinato

A
  • Inhibe la captura de I.
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12
Q

Tiamozol

A

Inhibe peroxidasa

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13
Q

Yodo radiactivo

A

Destruye el tejido tiroideo

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14
Q

Levotiroxina

A

T4 sintética

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15
Q

¿cuánto tiempo se pueden almacenar las hormonas tiroideas?

A

2-3 meses

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16
Q

Patologías

A
  • Hipotiroidismo primario→ T4 baja, t3 baja TSH alta
  • Hipotiroidismoo secundario → T4 baja, T3 baja, TSH baja
  • Hipertiroidismo primario → T4 alta, T3 alta, TSH baja
  • Hipertiroidismo secundarior → T4 alta, T3 alta, TSH alta
  • Sx de enfermo eutiroideo → Labs bien, pero presenta síntomas
  • Hipotiroidismo subclínico → Labs mal y no síntomas
17
Q

Receptore intracelular de la T3

A

RXR