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POD from G > 3.3, 3.4 DNA Viruses > Flashcards

3.3, 3.4 DNA Viruses Flashcards

1
Q

what type of genome are parvoviridae

A

ssDNA

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2
Q

are parvoviridae enveloped or non-enveloped

A

non-enveloped

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3
Q

what are the 3 main parvoviruses in veterinary medicine

A

canine parvovirus, feline panleukemia virus, porcine parvovirus

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4
Q

what 2 parvoviruses are genetically closely related

A

canine parvovirus and feline panleukemia virus

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5
Q

in what type of host cells are there receptors for parvoviruses

A

on epithelial cells

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6
Q

where do parvoviruses replicate and in what types of cells

A

in the nucleus of rapidly dividing cells

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7
Q

what causes the pathology observed in parvovirus infected animals

A

direct lysis/destruction of infected cells

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8
Q

in what two cell types do we see most canine parvovirus infection (2)

A

intestinal crypt epithelial cells and bone marrow progenitor cells

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9
Q

CPV-2 in utero or in less than 2 week old puppies can cause

A

myocarditis - sudden death

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10
Q

what are the signs of CPV-2

A

haemorrhagic diarrhea, vomiting, lymphopenia

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11
Q

what is the treatment for CPV-2

A

fluid/electrolytes; antibiotics

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12
Q

does feline panleukemia virus typically impact young or adult cats

A

yound

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13
Q

what is pronounced in feline panleukemia virus

A

severe and prolonged leukopenia

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14
Q

infection with feline panleukemia virus in the last 2 weeks of pregnancy to 2 weeks old causes

A

cerebellar hypoplasia and neonatal death

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15
Q

CPV-2 is usually diagnosed by _______ whereas feline panleukemia virus is usually diagnosed by _______

A

SNAP test; PCR

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16
Q

porcine parvovirus is associated with what in the sow

A

reproductive failure (SMEDI)

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17
Q

circoviruses:
______ genome
replicate in the _________
enveloped/nonenveloped

A

ssDNA; nucleus; nonenveloped

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18
Q

what type of virus is beak and feather disease virus (BFDV)

A

circovirus

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19
Q

what are the signs of BFDV in psittacine birds

A

necrotic or abnormally formed feathers

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20
Q

why do most BFDV birds die within 6-12 months

A

secondary infections

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21
Q

what are some diseases associated with porcine circovirus associated disease (PCVAD) (4)

A

dermatitis and nephropathy; post-weaning multisystemic wasting syndrome (PMWS); reproductive disease (abortions, SMEDI)

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22
Q

what lymphadenopathy is associated with PMWS (from PCVAD)

A

inguinal lymphadenopathy (other signs = anemia, jaundice, diarrhea, pallor)

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23
Q

Polyomavirus:
_____ genome
replicates in the __________
enveloped/non-enveloped

A

dsDNA; nucleus; non-enveloped

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24
Q

Budgerigar fledgling disease is caused by

A

polyomavirus

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25
Budgerigar fledgling disease has (low/high) mortality and is associated with (2) external signs and (2) post-mortem findings
high; absence of feathers; skin lesions; hemorrhage; pale musculature
26
papillomavirus: _______ genome enveloped/nonenveloped
dsDNA non-enveloped
27
pathology of papillomavirus is associated with what in animals
infectious papillomatosis (warts)
28
T/F canine papillomavirus is usually self-limiting
T
29
when would surgical excision be indicated in dogs with canine papillomavirus
impaired eating and breathing due to the location of the papillomatosis
30
herpesviruses: 1) type of genome 2) enveloped/nonenveloped
dsDNA; enveloped
31
how are herpesviruses spread
mucosal contact
32
what is a unifying aspect of the pathogenesis of herpesviruses
latency
33
in what locations does herpesviruses generally stay latent
neurons or lymphoid cells
34
what are the 3 groups of herpesviridae
alphaherpesvirinae, betaherpesvirinae, gammaherpesvirinae
35
what are the 4 alphaherpesvirinae
bovine herpesvirus 1, feline herpesvirus 1, equine herpesvirus 1, gallid herpesvirus 2
36
what is the betaherpesvirinae
suid herpesvirus 2
37
what are the 2 gammaherpesvirinae
ovine herpesvirus 2, alcelaphine herpesvirus 1
38
alphaherpesviruses: - rapid or slow growth - what type of lesions - where is the latent infection
- rapid - vesicular (epithelial cells) - sensory ganglia
39
what is another name for feline herpesvirus 1 and what disease is it clinically very similar to
feline rhinotracheitis; feline calicivirus
40
feline herpesvirus 1 (feline rhinotracheitis) is characterized by
upper respiratory disease
41
where is feline herpesvirus 1 (feline rhinotracheitis) common
shelters or multi-cat households
42
T/F vaccines for feline herpesvirus 1 (feline rhinotracheitis) exist
T
43
how is feline herpesvirus 1 diagnosed
PCR panel
44
what are 3 diseases caused by bovine herpesvirus 1
bovine rhinotracheitis, bovine vulvovaginitis, bovine enteritis
45
T/F bovine herpesvirus 1 can cause substantial mortality
T
46
how is bovine herpesvirus 1 diagnosed
PCR
47
what causes respiratory and genital lesions as seen in bovine herpesvirus 1 infection
focal epithelial cell necrosis
48
what is the most important viral cause of abortion in horses
equine herpesvirus 1
49
T/F equine herpesvirus 1 is not in Canada
F
50
how is equine herpesvirus 1 diagnosed
1) history of abortion 2) intranuclear inclusion bodies 3) PCR confirmation
51
what is a characteristic lesion of equine herpesvirus 1
foci of necrosis in the fetal liver (of the aborted foal)
52
what virus causes Mareks disease
GaHV-2 (gallid herpesvirus 2)
53
what species get gallid herpesvirus 2 (Mareks disease) and what cells are infected
birds (chickens, quails, turkeys); T lymphocytes
54
T/F Marek's disease is uncommon in Canada
F; common and ubiquitous
55
what is a consequence of Marek's disease infection
lymphoma due to T lymphoblastoid cell proliferation
56
what are the 4 forms that Marek's disease (Gallid herpesvirus 2) can form and which is the classifcal form
1) classical form -> nerves 2) ocular form -> iris 3) acute form -> nodules/tumors in organs and nerves 4) cutaneous form -> feather follicles
57
do betaherpesviruses have a long or short reproduction cycle and a long or short infection in culture
long; long
58
where do beta herpesviruses cause latent infection
secretory glands, lymphoreticular tissues, kidneys
59
what is another name for suid herpesvirus 2
inclusion body rhinitis
60
suid herpesvirus 2 (aka _____________) causes __________ in ____ old pigs
inclusion body rhinitis; mucopurulent rhinitis; 1-5 weeks
61
infection of pregnant sows with suid herpesvirus 2 (inclusion body rhinitis) causes
mummification, still birth, neonatal death
62
where do gammaherpesviruses cause latency
lymphocytes
63
T/F there is a vaccine for malignant catarrhal fever
F
64
outside Canada, malignant catarrhal fever is caused by ____________; within Canada, malignant catarrhal fever is caused by ____________
alcelaphine herpesvirus 1; ovine herpesvirus 2
65
what is a risk factor for malignant catarrhal fever
raising sheep and cattle in close proximity
66
what 4 parts of the body does malignant catarrhal fever infect
lymphoid tissue, respiratory, GI, CNS
67
poxviruses: - enveloped/non-enveloped - type of genome - where does it replicate (and where do we see inclusion bodies)
- enveloped - dsDNA - cytoplasm
68
capripoxvirus can be subdivided into
sheep and goat pox virus; lumpy skin disease
69
T/F sheep and goat pox virus and lumpy skin disease are endemic in Canada
F; never been found
70
T/F vaccination of capripox viruses exists
T
71
what are the main clinical signs of capripox virus infection (sheep and goat pox virus and lumpy skin disease)
- lesions on the skin and MM
72
parapoxvirus can be divided into what viruses
bovine papular stomatitis virus, orf virus
73
bovine papular stomatitis virus causes what lesions
papular and erosive lesions (muzzle, lips, mouth, teats)
74
T/F bovine papular stomatitis virus is zoonotic
T
75
what is an important DDx of foot and mouth disease
bovine papular stomatitis virus
76
where do we see orf virus lesiosn
mucocutaneous junctions (ex. lips)
77
T/F orf virus is zoonotic
T
78
what are the two forms of avipoxvirus (fowlpox virus)
cutaneous or diptheric
79
what causes the cutaneous form of fowlpox virus (avipox virus) and what is its clinical presentation
mosquito bite; skin lesions aka dry pox
80
what causes the diptheric form of fowlpox virus (avipox virus) and what is the clinical presentation
infection with droplets; wet pox on mucosa of larynx and mouth
81
T/F african swine fever is reportable in Canada but has never been reported
T
82
Asfivirus: - enveloped or non-enveloped - type of genome
- enveloped - dsDNA
83
what cells does african swine fever infect
macrophages and monocytes
84
T/F ticks are vectors of african swine fever virus
T
85
regarding the persistency of african swine fever: it is _________ and sensitive to lipid solvents but survives for many years in __________
thermolabile; refrigerated meat
86
what is the only known DNA arbovirus
african swine fever virus
87
acute african swine fever disease is characterized by
hemorrhagic disease
88
adenoviridae: - enveloped or nonenveloped - type of genome
- non-enveloped - dsDNA
89
T/F adenovirus infection is subclinical in most species
T
90
what important disease can adenovirus cause
infectious canine hepatitis
91
what is characteristic of canine adenovirus 1
1) hepatitis 2) corneal disease 3) respiratory disease
92
canine adenovirus 2 causes
respiratory disease

POD from G (46 decks)

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