3. Physiology of ANS Flashcards
Where are autonomic responses processed?
hypothalamus
In an autonomic reflex arc, the alpha-motor neuron (in skeletal muscle reflex arc) is replaced by ________.
autonomic nervous system
Is the ANS a 1 -neuron or 2-neuron pathway?
2-neuron pathway
- Pre-synaptic neuron: cell body (in CNS) terminates terminates in ganglion in periphery.
- Cell body (in the ganglion) terminates on the end organ.
In ANS, what neutrotransmitter is released by pre-ganglionic axon?
Acetylcholine
What type of receptors do post-gangliong cells express at the post-synaptic membrane?
nicotinic cholinergic receptors
Where do parasympathetics exit the CNS?
cranial and sacral
Where do sympathetics exit the CNS?
thoracic and lumbar
Where are parasympathetics located?
on/near target organ
Where are sympathetics located?
sympathetic chain
What do the yellow arrows indicate?
varicosities (boutons -or- en passant synapses)
What type of muscles are shown in this slide?
smooth muscle
Varicosities of the autonomics work the same as _____ of the NMJ.
pre-synaptic terminal
(Varicosities contain vesicles of NT, mitochondria, etc.)
In general, what is the difference between the post-synaptic side of synapse #1 and #2?
Ligand-gated receptors are spread out on the post-synaptic terminal.
What neurotransmitter is released from parasympathetic post-ganglionic (post-synaptic) axon?
Acetylcholine (binds to mAChr on target cells)
Muscarinic receptors are part of what family of receptors?
metabotropic (serpentine)
