3-Hemodynamics Flashcards

1
Q

laminar flow

A

streamlined, efficient flow
-parabolic bc slower/more friction/resistance close to vessel wall + highest velocity in middle

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2
Q

turbulent flow

A

irregular eddy currents with more shear stress on endothelial cells
-more energy to move blood
-thrombi more likely to devel

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3
Q

most important factor driving turbulent flow

A

velocity

blood flow = cross section area x velocity

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4
Q

atherosclerosis

A

narrowing vessels from plaque build up
-from turbulent flow
-hear bruits

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5
Q

law of laplace

A

wall tension = (transmural pressure x vessel radius) / wall thickness

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6
Q

inc wall tension from

A

transmural pressure + radius

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7
Q

thicker walls = ? tension

A

wall thickness dec wall tension bc better able to withstand

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8
Q

wall tension balanced by

A

elastic + smooth muscle in vessels

if mismatch then rupture/aneurysm

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9
Q

aneurysm

A

wall tension inc as vessel radius inc + transmural pressure inc = rupture

can be undetectable with just inc wall tension and radius until the pressure maximizes

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10
Q

most prominent effect on flow

A

vessel radius

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11
Q

artery structure

A

large lumen + thick walls

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12
Q

arterioles structure

A

small lumen + thick innvervated wall

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13
Q

capillaries structure

A

smallest lumen + very thin walls (1 cell)

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14
Q

venules structure

A

small lumen + thin walls

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15
Q

vein structure

A

large lumen + thick walls

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16
Q

arterials as resistors

A

small changes in volume = large shift in pressure

17
Q

venous as capacitors

A

small changes in pressure = large shift volume

18
Q

venous compartment

A

largest volume of blood
-pressure direct to blood amount

if veins constrict then more vol pushed into circulation back to heart (symp stim)

19
Q

flow =

A

change in pressure / resistance

direct relation, move same direction

20
Q

if constant flow then ? velocity

A

velocity dec as total cross sectional area inc

why aorta has highest velocity bc smallest total cross section

21
Q

where pressure drop is greatest

A

across arteriolar compartment, corresponds with inc resistance

22
Q

arteriolar vasodilation = ? flow

A

inc capillary pressure and blood flow

23
Q

arteriolar vasoconstriction = ? flow

A

dec capillary pressure and blood flow
-inc afterload in LV

24
Q

resistance differences

L and R

A

left heart = systemic circulation resistance is 1 TPR
right heart = pulmonary circulation resistance is 0.1

total resist of systemic circ x10 higher than pulmonary

25
velocity trends
1. highest in large arteries 2. drops dramatically as approach capillaries 3. rise slowly towards veins
26
volume trends
1. highest in capacitor vessels of veins 2. lowest in high resistance structures (arterioles and caps)
27
pressure trends
1. highest in arteries and arterioles 2. lowest in veins
28
resistance trends
1. peaks in arterioles 2. low in arteries, caps, and veins