Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Paediatrics > 3: Cardio - Kawasaki Disease > Flashcards

3: Cardio - Kawasaki Disease Flashcards

1
Q

What is Kawasaki disease referred to as

A

Mucocutaneous Lymph Node Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Kawasaki disease

A

Febrile vasculitis - predominantly affecting coronary and medium size vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which age-group does Kawasaki disease occur

A

Under 5’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What gender is Kawasaki disease more common in

A

Males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What ethnicity does Kawasaki disease occur in

A

Asians

Afro-carribeans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most common cause of acquired heart disease in developed countries

A

Kawasaki Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the most common cause of acquired heart disease in developing countries

A

Rheumatic Fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is a mnemonic to remember symptoms of Kawasaki disease

A

CRASH and burn

Conjunctivitis 
Rash
lymphAdenopathy
Strawberry tongue
Hand + feet - red

Burn: Fever >5d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the criteria for Kawasaki disease

A

Need 5-out-of-6 of the following:

  1. Fever >5d
  2. Oropharyngeal mucositis
  3. Lymphadenopathy
  4. Polymorphous Rash
  5. Bilateral, Non-purulent conjunctivitis
  6. Red hand + feet - lead to desquamatisation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How long should the fever last in Kawasaki disease

A

5d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are three symptoms/signs of oropharyngeal mucositis

A
  • Red pharynx
  • Strawberry tongue
  • cracked red lips
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What type of conjunctivitis is present in Kawasaki disease

A

Bilateral, non-purulent conjunctivitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What type of rash is present in Kawasaki disease

A

Polymorphous rash - which originates on the trunk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where does the rash in Kawasaki disease originate

A

The trunk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the mneumonic to remember symptoms of Kawasaki disease

A

CRASH and BURN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are three non-specific features of Kawasaki disease that may precede classical symptoms

A

Abdominal pain
Diarrhoea
Faitgue

17
Q

When should Kawasaki disease always be considered

A

If child has rash and high temperature that is not responding to Abx

18
Q

Explain pathophysiology of Kawasaki disease

A
  • Autoimmune damage to vessels exposes TF on the endothelium of medium-size and coronary arteries
  • This triggers the coagulation cascade leading to thrombosis
  • Of coronary vessels this can cause MI
  • Damage to artery walls causes weakening that can lead to aneurysms - may rupture
  • Damage and healing by fibrosis also results in stenosis
19
Q

How is Kawasaki disease diagnosed

A

Clinical diagnosis, supported by investigations

20
Q

What investigations may be ordered in Kawasaki disease

A
  1. ESR/CRP
  2. FBC
  3. Anti-endothelial cell antibodies
  4. ECHO
21
Q

How will ESR and CRP present in Kawasaki disease

A

Raised

22
Q

How will FBC present in Kawasaki disease

A

Leucocytosis

Thrombocytosis

23
Q

Why is an ECHO required in Kawasaki disease

A

Evaluate for coronary aneurysms

24
Q

What is given to manage Kawasaki disease

A
  1. IVIG
  2. High-dose Oral aspirin
  3. IV Glucocorticoids
25
Q

When should IVIG be given in Kawasaki disease

A

Within 10d

26
Q

What is the advantage of giving IVIG within 10d in Kawasaki disease

A

Reduces risk of coronary artery aneurysms

27
Q

What is the only exception to give aspirin to children under 16

A

Kawasaki disease

28
Q

Why is aspirin not normally given to children under 16y

A

Risk of Reye’s syndrome

29
Q

When is IV Glucocorticoids given in Kawasaki disease

A

High risk patients or refractory disease

30
Q

How long does Kawasaki disease take to resolve

A

6-8W

31
Q

What is the main risk of Kawasaki disease

A

Coronary artery aneurysms - more common 2-3W in

32
Q

What are 3 other cardiac risks of Kawasaki disease

A

MI
Arrythmias
Myocarditis

Paediatrics (61 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions