2: Paediatric MSK - JIA, Rickets, DDH, Leg-Calve Perthes, Slipped Upper Epiphyseal Plate, Transient Synovitis, Osgood Schlatter's Flashcards
What is juvenile idiopathic arthritis
Onset of rheumatic joint disease before age of 16. Involving joint inflammation for more than 6 weeks
Why is a timeframe of 6W set on JIA
To differentiate from septic arthritis
What age-group does JIA occur in
<16Y
What gender is JIA more common in
Females
What is the most common for of JIA
Oligo-articular JIA
What is oligoarticular JIA
JIA affecting less than 4 joints within 6 months
What joints are affected first in oligoarticular JIA
large weight-bearing joints
What is associated with oligoarticular JIA
anterior uveitis
How will oligoarticular JIA present on blood tests
- Raised ESR/CRP
- -ve RF
- positive ANA
How will seronegative polyarticular JIA present
affects more than 5 joints within 6 months of onset
How will polyarticular JIA present on blood tests
- Raised ESR/CRP
- -ve RF
- positive ANA
What blood test is positive in seropositive polyarticular JIA
Positive RF
What is systemic JIA called
Still’s disease
In which age group is Still’s disease more common
2-4y
What is the clinical criteria for stills disease
Must have
- More than one joint involved
- Intermittent fever for at least 2W, with T spikes on at least 3d
- One extra-articular manifestation
What are extra-articular manifestations of stills disease
- Salmon pink rash
- Lymphadneopathy
- Hepatosplenomegaly
- Serositis
How will arthritis present in still’s disease
Red swollen joint
Early morning stiffness
Limited/painful movement
Who manages JIA
Paediatric rheumatology
Describe management of JIA
- Physio
- Encourage swimming/cycling
- Orthoses
- Naproxen
- Intra-articular corticosteroid injections
What is the prognosis of JIA
95% resolves by puberty
What are 4 complications of JIA
- Serositis (pericarditis, pleuritis)
- Growth retardation secondary to premature epiphyseal plate closure
- Chronic anterior uveitis
- Leg-length discrepancy
In a child 0-5y what are the causes of a limp affecting the back
Discitis
In a child 0-5y what are the 3 causes of a limp affecting the hip
- Transient synovitis
- Developmental dysplasia
- Septic arthritis
In a child 0-5y what is a causesof a limp affecting the femur
- Osteomyelitis
In a child 0-5y what is a cause of a limp affecting the knee
- Septic arthritis
In a child 5-10y what are the 3 causes of a limp affecting the hip
- Transient synovitis
- Perthe’s disease
- Septic arthritis
In a child 5-10y what are the 2 causes of a limp affecting the knee
- Discoid meniscus
- Septic arthritis
In a child 10-15y what are the 2 hip
- Septic arthritis
- Slipped upper epiphyseal disc
In a child 10-15y what are the 3 conditions causing limp at the knee
- Osgood schlatters
- PFP syndrome
- Osteochondritis dessicans
What is the commonest cause of a child with a limp
Trauma
What age is septic arthritis more common
<2
How will septic arthritis present
- Affects single synovial joints
- Erythematous, warm, swollen joint
- Child may present with a limp
What is osteomyelitis
- Infection of metaphysic of long bone
How will child present with osteomyelitis infection
- febrile, painful and immobile limb. Overlying skin may be swollen, hot and erythematous.
What is the commonest cause of paediatric hip pain
transient synovitis
What age group does transient synovitis occur
2-12
How will transient synovitis present
- Afebrile
- Acute hip pain on movement, that is ok on rest
What condition is juvenile idiopathic arthritis associated with
Chronic anterior uveitis
What should be done to prevent blindness in JIA
Regular eye screening
Why may children with JIA have growth retardation
Chronic inflammation can cause stiffening and deformity of the joints.
Also chronic disease - present with frequent infections, malnutrition, stress and corticosteroid use.
Define rickets
Poor bone mineralisation prior to fusion or epiphyseal plates
What is poor bone mineralisation after epiphyseal fusion called
Osteomalacia
What cause rickets
Deficiency in vitamin D:
- Malnutrition - low vitamin D diet
- Poor sunlight exposure
- Malabsorption
- Impaired hydroxylation: liver or kidney disease
- Congenital defect in metabolism
Does breast milk have a high or low vitamin D concentration
Low
What can cause malabsorption of vitamin D
Coeliac Disease
What is the clinical presentation of Ricket’s disease
- Bending of long bones
- Knocked Knees
- Bow legs
- Harrison groove
- Rachitic rosary
- Marfan’s sign
What is rachitic rosary
Distention of bone-cartilage junction at ribs
What is marfans sign
Increase space between bone-cartilage junctions
What is Harrison groove
Softened lower rib are pulled in by the diaphragm causing a groove at thoracic outlet.
Explain normal vitamin D processing
- Cholecalciferol (D3) is ingested or made in the skin by converting UVB
- Liver hydoxylates D3 to 1-OH vitamin D
- Kidney hydroxylates D3 to 1,25 di-OH vitamin D3
- Vitamin D deficiency results in decrease mineralisation and hypocalcaemia. Causing PTH release
What is first-line investigation of vitamin D deficiency
Bone profile
What will be seen on bone profile in Ricket’s
- Low vitamin D
- Hypocalcaemia
- Raised ALP
What is second-line investigation of ricket’s
X-Ray
What will be seen on x-ray in ricket’s disease
Cupped, ragged, metaphyseal edges
How is ricket’s disease managed
Cholecalciferol: vitamin D3 (5,000- 10,000 IU)/day
What is a limp
abnormal gait pattern due to weakness, pain or deformity
What is discitis
infection of IV disc
How will discitis present
- Fever
- Irritable
- Back pain
- Not willing to walk
What are investigations for discitis
FBC
CRP/ESR
MRI
What is developmental dysplasia of the hip
Acetabular Dysplasia
What age range does DDH occur
0-5y
What gender is DDH more common
Girls (4:1)
If under 4 months how should DDH be investigated
USS
If over 4 months how should DDH be investigated
X-ray
What is septic arthritis
Infection of a synovial joint
What organism is the most common cause of septic arthritis
Staph.A
If a spinal fracture presents in an infant up to 9 months-old, what should be suspected
Non-accidental injury
If non-accidental injury is suspected what should be done
Refer for skeletal survey
What is transient synovitis of the hip also known as
Irritable hip
What age-range does transient synovitis of the hip occur
2-12
In which gender is transient synovitis of the hip more common
Male (2:1)
How will transient synovitis of the hip present
- URTI in recent weeks
- Pain in the hip on movement absent at rest
- Afebrile
What is Leg Calve Pethes Disease
Avascular necrosis of the femoral head
What age group does LCP disease occur
4-10
How will LCP present
- Hip pain that radiates to the knee
What is slipped upper femoral epiphyseal
Posterior-inferior displacement of femoral head to femoral neck and growth plate
What age range does slipped upper femoral epiphysis occur
10-16
How will slipped upper epiphyseal plate present
Dull pain in the hip, groin or knee
What is Osgood-Schlatter disease
Over-use of quadriceps during growing period leads to increase traction through patella ligament - causes tibial tuberosity apophysitis
What age group does Osgood Schlatter disease occur
9-14
How will Osgood-Schlatter schlatter disease present
Anterior knee pain worse on activity
What is a mnemonic to remember causes of limping child
STOP LIMPING
What are the causes of a limp in a child
Septic arthritis Trauma Osgood schlauer Perthes Leg length discrepancy Inflammatory - transient synovitis Malignancy Pyomyositis Illiopsoas abscess Neurological Gullian barre, GI (torsion, appendicits)
When should a child with a limp be referred for urgent assessment
- <3Y
- > 9Y with reduced internal rotation
- Suspect NAI
- Red flags of malignancy
- Unable to weight bear
Why is a child less than 3 urgently referred
suspected septic arthritis
Why is a child older than 9 with reduced internal rotation urgently referred
slipped upper femoral epiphyseal disc is suspected
When should a same-day x-ray be carried out in limping children
No indications urgent assessment.
History trauma
Localised bony tenderness
What is DDH
Hip instability, subluxation and dislocation of femoral head
In which gender is DDH more common
Females (5:1)
What signs are positive in DDH in infants <6m
Barlow
Ortolani sign
How will a child 6-18m with DDH present
- No Barlow or ortolans sign
- Unable to abduct hip
- Asymmetrical gluteal folds
How will a child, older than 18 months, with DDH present
- Leg length discrepancy
- Hip pain referred to anterior thigh
- Trendelenburg gait
What is a distinguishing feature of children with bilateral DDH
they will not have leg length discrepancy
How is DDH typically identified
Newborn baby check
When is screening for DDH recommended
If a child has one or more RF:
- FH
- Features DDH
- Breech
What is main investigation for DDH if child is under 4 months
USS
What is used to investigate DDH if child is older than 4 months
X-Ray
If less than 6 months how is DDH managed
Palvik Harness
How does palvik harness hold the hips
- 90-100’ flexion
- 50’ abduction
How is DDH 6-18m managed
Closed reduction + immobilisation
How is DDH >18m managed
Open reduction + immobilisation
What is Legg Calve Perthes Disease
Idiopathic avascular necrosis of the femoral head
What age range does legg calve perves disease occur
4-10
What gender is Legg calve perves disease more common
Male
How will LCP disease present
Hip pain that radiates to anterior knee
What is first-line investigation for LCP disease
x-ray
What is problem with x-ray in LCP disease
no findings in first-3m
How is LCP disease on x-ray graded
lateral pillar classification
What are poor prognostic indicators in LCP
lucency femoral head
increased joint space
What are the two options for managing LCP disease
- Conservative
2. Surgical
When is conservative management preferred in LCP disease
Child <6
Lateral Pillar A
Undamaged femoral head
What is conservative management of LCP disease
Physiotherapy
Reduced weight bearing
When is surgical management of LCP disease preferred
Child >8
Lateral Pillar B/C
Damaged femoral head
How is LCP disease managed surgically
Femoral Osteotomy
What is a complication of LCP disease
Secondary OA
What is slipped capital femoral epiphysis
posterior and inferior displacement of the femoral head relative to femoral neck and growth plate
What is the most common hip disorder in adolescents
slipped capital femoral epiphysis
what age range does slipped capital femoral epiphysis happen
10-16
which gender is slipped capital femoral epiphysis more common
Males
what are 5 risk factors for slipped capital femoral epiphysis
Obesity Trauma Hypothyroid Down syndrome FH
what are the two types of slipped capital femoral epiphysis
chronic and acute
how will slipped capital femoral epiphysis present clinically
- dull ache in medial thigh, knee, hip or groin.
- limited movement on internal rotation
why will children with slipped capital femoral epiphysis have knee pain
due to referred pain form obturator
what is a sign of slipped capital femoral epiphysis
reduced internal rotation - may hold leg in external rotation
what is first line investigation for slipped capital femoral epiphysis
x-ray
how will x-ray appear in slipped capital femoral epiphysis
- Widening joint space
- Displacement femoral head inferior and posteriorly
what is management for slipped capital femoral epiphysis
- Avoid weight bearing
- Surgical fixation
what are two problems of slipped capital femoral epiphysis
Avascular Necrosis
OA