29.Reteta: Anemie megaloblastica, 30 ani, tratament intretinere Flashcards

1
Q

Rp1/2

A

Rp1/Ciancobalamina f 50 µg
F nr II (doi)
DS im 1 fiola la 2 saptamani, 30 zile
#
Rp2/Acid folic dj 5 mg
AO nr I (unu)
DS oral 3x1 dj/zi, 1 luna

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

1.Clasificare

A

Ciancobalamina – antianemic (Vitamina B12)
Acid folic – antianemic, vitamina B9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
  1. F farmaceutica + doza+cale
A

Ciancobalamina fiole 50 µg/mL, 1000µg/mL, i.m. , s.c.

Acid folic dj 5 mg (oral); gravida: 1dj/zi in lunile ce preced conceptia; adulti: 3x1 dj/zi, oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3.Actiune FD

A

Ciancobalamina:
-Esențială pentru maturarea eritrocitelor
- sprijina diviziunea celulara eficienta
-alimenteaza celulele progenitoare ale eritrocitelor cu cant necesara de vitamina B12

Acid folic:
-ajuta la maturarea eritrocitelor în măduva osoasă
-acționează sinergic cu vit B12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

4.Indicatii terapeutice

A

Ciancobalamina:
 anemie megaloblastiaca; prin carenta de B12
 tulburari neurologice, neuropatii
 hepatite cronice si ciroza

Acid folic:
 anemia megaloblastica prin deficit de acid folic
 profilactic in sarcinaimpiedica aparitia spinei bifide la fat
 profilaxia si tratamentul toxicitatii Metotrexatului
 anemii hemolitice cronice severe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

5.Efecte adverse

A

Ciancobalamina:
rar alergie, e bine tolerata, in doze mari urina e rosie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

6.Contraindicatii

A

Ciancobalamina: in tumori maligne;
acid folic: impreuna cu chimioterapice antimicrobiene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly