17.Reteta:HTA, III, insuficienta renala

Question 1

Rp 1/ 2

Answer 1

Rp1/Amlodipina cpr 10 mg
AO nr I (unu)
DS oral 1 cpr/zi , 30 zile
#
Rp2/Furosemid cpr 40 mg
AO nr I (unu)
DS oral 1 cpr/zi, dimineata, 30 zile

Question 2

1.Clasificare

Answer 2

Amlodipina – blocant canale Ca (antihipertensiv, antiaritmic)

Furosemid – antihipertensiv, diuretic de ansa

Question 3

2.Forma farmaceutica + doza + mod de adm

Answer 3

Amlodipina cpr 5mg, 10 mg (oral)

Furosemid cpr 40 mg (oral), fiole 20mg/2ml, 40mg/4ml, 250mg/2ml, dimineata

Question 4

3.Actiune FD

Answer 4

Amlodipina: VD cu scadere RVP si TA
 creste FSR (de aceea se da in HTA + IR)
 actiune antianginoasa, antiaterogenă
 actiune antiHTA, pt ca produc VD arteriala

Furosemid: inhiba reabs tubulara de Na+, K+,Cl- la nivelul Ansei ascendente Henle

Question 5

4.Indicatii terapeutice

Answer 5

Amlodipina (are tropism vascular):
 cardiopatia ischemica, in angina pectorala instabila
 HTA usoara ca monoterapie
 Sd Raynaud
 spasme cerebrale vasculare dupa hemoragie subarahnoidiana

Furosemid:
 criza hipertensiva, Insuf Renala
 edeme din ciroza hepatica si Sd nefrotic, IC grava

Question 6

5.Efecte adverse

Answer 6

Amlodipina: edeme, cefalee, oboseala, ameteli, bufeuri de caldura

Furosemid: scade K+, deshidratare, surditate trecatoare, creste Acid uric si Glicemia

Question 7

6.Contraindicatii

Answer 7

Amlodipina
 stenoza de aorta
 sarcina si alaptare
 insuficienta cardiaca clasa NYHA lll si IV
 angina pectoral instabila, IMA, in primele 4 sapt

Furosemid:
hipovolemie sau deshidratare, hipokalemie si hiponatriemie severe