25. Reteta: Anemie feripriva, 45 ani, 50 kg, Hb= 10g/dl Flashcards

1
Q

Rp 1/ 2

A

Doza de Fe= 4,4 * 50 * (16-10) = 1320 mg = 1,32g fier

Rp1/Ferrogradumet, cpr cu elib prelungita 105 mg
AO nr I (unu)
DS oral, 1 cpr/zi, dimineata inainte de masa, 12 zile
#
Rp2/Vitamina C cpr 200 mg
AO nr IV
DS oral 1cpr/zi, dimineata, 4 luni

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2
Q

1.Clasificare:

A

Ferrogradumet (Sulfat feros) - antianemic, fier administrat pe cale orala
Vitamina C – impreuna cu preparatul de fier creste absorbtia Fe2+

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3
Q

2.Forma farmaceutica + doza + mod de adm, ritm:

A

Ferrogradumet:
cpr prelungite 105 mg; adulti: 1cpr/zi; oral, dimineata pe stomacul gol

Vit C:
Comprimate orale: 100 mg, 200 mg, 500 mg, 1000 mg
Pulbere diz: 1g/plig
Solutie injectabilă: 100 mg/ml sau 500 mg/ml
-dimineata

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4
Q

3.Actiune FD:

A

-Fe intra in constitutia Hb cu efect ANTIANEMIC, rol catalitic in respiratia celulara si intervine in nutritia epiteliilor
-utilizat pentru a completa rezervele de fier din organism, necesare pentru formarea globulelor roșii

Vit C:
-Crește absorbția fierului non-hemic

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5
Q

4.Indicatii terapeutice:

A

Ferrogradumet:
 anemia feripriva fiziologica in sarcina, la adolescent, donator de sange
 anemia feripriva patologica prin malabsortie, menoragie
 hemoragie de cauza oculta - ulcer peptic, cancer gastro-intestinal

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6
Q

5.Efecte adverse:

A

Ferrogradumet:
 la adm orala: greturi, colorare in brun a dintilor, iritație gastrică, scaun negru, constipatie
 toxicitate acuta apare accidental la copii: greturi, varsaturi, diaree, hipotensiune arterial, coagulopatie, insuficiente multiple de organe si SOC -> tratam: spalaturi gastrice + antidot: Deferoxamina
 toxicitate cronica: hemocromatoza, hemosideroza (cand se inj prea mult Fe2+)

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7
Q

6.Contraindicatii:

A

Ferrogradumet: hemocromatoza, hemosideroza, anemie hemolitica

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