20. Reteta: Insuficienta cardiaca cronica + insuficienta renala cronica Flashcards

1
Q

Rp 1 si Rp 2

A

Rp1/Digitoxina sol 1mg/ml
AO nr I (unu)
DS p.o 1x5 pic/zi, 6zile/saptamana, dimineata, 30 zile
#
Rp2/Furosemid cpr 40 mg
AO nr I (unu)
DS oral 1 cpr/zi, dimineata, 30 zile

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2
Q

1.Clasificare

A

Digitoxina - tonicardiac direct, cardiotonice steroidiene- digitalice
Furosemid - antihipertensiv, diuretic de ansa

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3
Q
  1. Forma farmaceutica + doza
A

 Digitoxina flacon cu 10ml, 1mg/ml sau 50 picaturi (oral)

 Furosemid cpr 40 mg (oral), fiole 20 mg/2ml, 40mg/4ml

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4
Q

3.Act FD

A

Digitoxina:
efect inotrop +, batmotrop +
efect cronotrop-, dromotrop-
efect diuretic prin cresterea FG
Pe vase: scade RVP, tonusul venos si Fluxul sangvin creste

Furosemid:
inhiba reabs tubulara de Na+, K+,Cl- la nivelul Ansei ascendente Henle

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5
Q

4.Indicatii terapeutice

A

Digitoxina:
-insuficienta cardiaca acuta
-insuficienţa cardiacă congestivă cronică cu
fibrilaţie atrială rapidă
- tulburari de ritm: fibrilatie, flutter atrial, TPSV

Furosemid: criza hipertensiva, Insuf renala
edeme din ciroza hepatica si Sd nefrotic, IC grava;

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6
Q

5.Efecte adverse

A

Digitoxina: Intoxicatia cu digitala:
 tulb neuro-psihice: cefalee, somnolenta, fatigabilitate, confuzii, convulsii, halucinatii
 anorexie, greata, varsaturi, dureri abdominale

Furosemid: scade K+, deshidratare, surditate trecatoare, creste Acid uric si Glicemia

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7
Q

6.Contraindicatii

A

Digitoxin:
absoluta – intoxicatia digitalica
-relative: bradicardie, BAV, tulburari de ritm ventric, IC prin disfunctie diastolica

Furosemid: hipovolemie sau deshidratare, hipokalemie si hiponatriemie severe

în Insuf Renala se adm: IECA, sartani, Spironolactona

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