2016 biochem Flashcards
Which IF adds aa-tRNA to the P site of the ribosome?
a. IF1
b. IF2
c. IF3
d. IF4
b. IF2
In a PCR 20 cycles, what is the number of products for a single DNA strand (only one primer used)?
a. 20
b. 40
c. 60
d. 80
a. 20
Deficiency of Vit C and Cu will result in dysfunction in what part of collagen structure?
a. Hydroxylation and cross-linking
b. Methylation and phosphorylation
a. Hydroxylation and cross-linking
What characterizes CFJ syndrome?
a. increased prion beta sheets
b. increased prion phosphorylation
a. increased prion beta sheets
what stabilizes a primary protein structure?
a. Glycosyl bonds
b. S-S bonds
c. S-H bonds
d. peptide bonds
d. peptide bonds
how are isozymes and enzymes related?
a. They catalyze the same reaction
b. They use the same cofactors
c. They use the same reversible inhibitors
a. They catalyze the same reaction
What enzyme is involved in uric acid synthesis?
xanthine oxidase
Which pair of products would be most likely produced by catabolic pathway?
a. ADP, NADH
b. ATP, NAD+
c. ATP, NADH
d. ADP, NAD+
c. ATP, NADH
What is a characteristic of mRNA editing?
a. tissue-specific
b. 2 identical proteins
c. activation of phosphorylation
d. transcription regulation
a. tissue-specific
What type of mutation in coagulation factor 8 causes severe hemophilia type A?
a. inversion
b. missense
c. single
d. duplication
a. inversion
Farnysl and farnsyl give us what in cholesterol synthesis?
a. 5-Pyrophospho-mevalonate
b. IPP
c. Mevalonate
d. Squalene
d. Squalene
What is the repair mechanism affected in hereditary nonpolyposis colon cancer?
a. Nucleotide Excision Repair
b. Base excision repair
c. Mismatch repair system
c. Mismatch repair system
What’s the structure of histones in a nucleosome?
a. Octomer
b. Tetramer
c. Hexamer
d. Dimer
a. Octomer
Which of these is the target of restriction endonuclease?
a. Double strand DNA
b. Single strand DNA
c. Double strand RNA
d. Single strand RNA
a. Double strand DNA
Which nucleoside activates RAS protein?
a. ATP
b. CTP
c. GTP
c. GTP
Which DNA polymerase has 5’ to 3’ exonuclease activity?
a. I
c. II
b. III
a. I
What is the rate limiting enzyme of converting triglycerides to free fatty acid?
a. adipose triglyceride lipase (ATGL)
b. hormone sensitive lipase (HSL)
c. mono glyceride lipase (MGL)
b. hormone sensitive lipase (HSL)
What activates LCAT?
a. Apo A
b. Apo B
c. Apo C
d. Apo D
a. Apo A
What is the major component of lipid raft?
a. cholesterol
b. TAG
a. cholesterol
What is used to make ketone bodies in prolonged (>21days) starvation?
a. Lactate from RBCs
b. fatty acid from adipose tissue
c. long chain amino acids from skeletal muscles
d. glycerol from adipose tissue
b. fatty acid from adipose tissue
What is used as a cofactor for transamination reaction?
Pyridoxal phosphate
Respiration ratio of isolated mitochondria was measured as the concentration of oxygen. What should be added to reduce the respiration ratio (decrease oxygen)?
a. ATP
b. NAD+
c. FAD
d. ADP
d. ADP
Which of the following happens when lactate is failed to be exported from the muscles?
a. glycolysis stops in muscles
b. gluconeogenesis stops in liver
c. oxidation of lactate to pyruvate
d. fatty acid synthesis/ oxidation stops
a. glycolysis stops in muscles
