2013 biochem Flashcards
Which of the following has a role in mRNA splicing?
A. SnoRNA
B. SnRNA
C. Ribozymes
B. SnRNA
What is true about collagen protein?
A. Highly carboxylated
B. Highly glycosylated
C. Highly hydroxylated
C. Highly hydroxylated
Which of the following activates PPP? A. NAD B. AMP C. NADP D. NADPH
C. NADP
What’s the change that occurs in prion disease?
A. Increased Beta sheets
B. Increased alpha Helices
A. Increased Beta sheets
Protein kinases add phosphates on which of the following amino acid residues?
A. Serine
B. Lysine
A. Serine
A High-affinity competitive inhibitor has a resemblance to which of the following structures? A. Allosteric effector B. Substrate C. Product D. Cofactor E. Transition state
E. Transition state
What is the structural motif in the DNA binding domain of the intracellular glucocorticoid receptor?
A. Leucine zipper
B. Helix-turn-helix
C. Zinc finger
C. Zinc finger
What is the target sequence in lysosomal proteins?
A. Mannose 5-phosphate
B. Mannose 6-phosphate
B. Mannose 6-phosphate
A patient with hypertriglyceridemia has normal lipoprotein lipase. What should be checked next? A. ApoE B. ApoA-II C. ApoC-I D. ApoC-II
D. ApoC-II
A deficiency in which of the following causes hypocholesterolemia? A. ApoC-II B. ABC C. ApoE D. CETP E. LDL receptor
B. ABC
In order to measure free (unesterified) cholesterol in the plasma, what should be included?
A. Cholesterol oxidase
B. Cholesterol oxidase + cholesterol peroxidase
C. Cholesterol esterase + cholesterol oxidase
D. Cholesterol peroxidase
B. Cholesterol oxidase + cholesterol peroxidase
measure free cholesterol= cholesterol oxidase + cholesterol peroxidase
measure total cholesterol= cholesterol oxidase + cholesterol peroxidase + cholesterol esterase
What causes acidosis in prolonged starvation?
A. Ketone bodies
B. Fatty acid oxidation
C. Gluconeogenesis
A. Ketone bodies
Which lipid is abundant in skin?
A. Ceramide
B. Sphingolipid
A. Ceramide
Where are desaturases located inside the cell? A. Golgi apparatus B. nucleus C. Endoplasmic reticulum D. Mitochondria
C. Endoplasmic reticulum
Where are S-S disulfide bonds formed? A. Golgi apparatus B. Nucleus C. Mitochondria D. Endoplasmic reticulum
D. Endoplasmic reticulum