2014 I&I Flashcards

1
Q
Which of the following is the treatment of congenital listeriosis?
A) Cefoxitin
B) Cefuroxime
C) Ampicillin
D) Cloxacillin
A

C) Ampicillin

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2
Q

What characterizes congenital listeria monocytogenes?
A) Granuloma infantiseptica
B) Persistent rhinitis (snuffles)
C) Cerebral calcification

A

A) Granuloma infantiseptica

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3
Q
What is the antibiotic that is used as a prophylaxis for intra-abdominal surgeries? 
A) Cloxacillin
B) metronidazole
C) Benzylpenicillin
D) Rifampicin
A

B) metronidazole

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4
Q

What microorganism causes food poisoning 30 hours after ingesting sea food?

A

Vibrio parahemolyticus

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5
Q

What is used to sterilize plastic material?
A) Ethylene oxide
B) Hypochlorite
C) Alcohol

A

A) Ethylene oxide

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6
Q

What makes the thymus indifferent for lymph-borne antigens?
A) Lacking germinal centers
B) Blood thymus barrier
C) Not having afferent lymph vessels

A

C) Not having afferent lymph vessels

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7
Q
What is the treatment of influenza A in case of Oseltamivir resistance?
A) Amantidine
B) Zanamivir
C) Saquinavir
D) Acyclovir
A

B) Zanamivir

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8
Q
What vaccine can you take during pregnancy? 
A) Diphtheria toxoid 
B) Tetanus toxoid  
C) Measles vaccine 
D) Rubella vaccine
A

B) Tetanus toxoid

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9
Q
If a disease has a basic reproductive rate of 20 what % of the population needs to be immune to prevent an epidemic?
A) 5-15%
B) 25-45%
C) 55-75%
D) 95-99%
A

D) 95-99%

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10
Q

What is the mechanism of action of Maraviroc?
A) Incorporate into viral DNA, causing chain-termination
B) Blocks translation of viral mRNA into viral
protein.
C) Inhibits 5’cap formation of mRNA
D) Binds to CRC5 to block viral entry

A

D) Binds to CRC5 to block viral entry

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11
Q

What is the effect of HIV on lymphoid tissues?
A) Follicular hyperplasia in the early stage, then involution
B) Lymph nodes hyperplasia

A

A) Follicular hyperplasia in the early stage, then involution

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12
Q

What is expected after administration of antiretroviral therapy?
A) CD4 T cell count & viral load both increase
B) CD4 T cell count decrease and viral load increases
C) CD4 T cell count increases, depression of viral load

A

C) CD4 T cell count increases, depression of viral load

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13
Q
Inhalation of which of the following types of spores results in mucormycosis?
A) Blastospores 
B) Sporangiospores 
C) Macrospores 
D) Chlamydospores
A

B) Sporangiospores

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14
Q
What is the cause of insulin-resistant diabetes mellitus?
A) Release of Sequestered Auto-antigens
B) Cytokine imbalance 
C) Defects in T cell Immunoregulation
D) Overexpression of MHC2
A

D) Overexpression of MHC2

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15
Q

How do viruses evade the immune system?
A) Prevent the action of Fas
B) High Fas activation
C) Lower telomerase activity

A

A) Prevent the action of Fas

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16
Q

Which of the following microorganism is the most associated with catheter-related infections?
A) Staphylococcus pyogens
B) candida albicans
C) Staphylococcus epidermidis

A

C) Staphylococcus epidermidis

17
Q
How to visualize cell surface antigens from a tissue section?
A) Precipitation
B) Immunofluorescence
C) ELISA
D) Radioimmunoassay
A

B) Immunofluorescence

18
Q

Which of the following viruses is transmitted through tattooing and sexual contact?
A) Hepatitis B virus
B) hepatitis A virus
C) herpes simplex virus

A

A) Hepatitis B virus

19
Q
Which of the following fungus requires oil supplementation for its growth?
A) Malesezzia furfur
B) candida alopecia 
C) rhizopus
D) candida albicans
A

A) Malesezzia furfur

20
Q
Why are viruses not affected by cytokines?
A) Degradation of cytokines
B) Lack of cytokines receptors
C) Neutralizing cytokines
D) Cytokine size is small
A

B) Lack of cytokines receptors

21
Q
Which of the following processes is part of innate immunity?
A) NK-mediated killing
B) ADCC
C) Cytotoxic T cells
D) IgG binding and neutralization
A

A) NK-mediated killing

22
Q

Radio-labelling of white blood cells in order to be used in imaging depends on which pathophysiological process?
A) migration of leukocytes to infection site
B) unable to move the limbs cause of swelling

A

A) migration of leukocytes to infection site

23
Q
For which of the following viruses a hyper immunoglobulin vaccine is used as prophylaxis after exposure?
A) VZV
B) Hepatitis A
C) Parvovirus
D) Yellow Fever Virus
A

A) VZV

24
Q

What is the vaccine that is used for health care workers who perform exposure-prone procedures?
A) HBV vaccine
B) Rabies Virus Vaccine
C) Hepatitis A Virus Vaccine

A

A) HBV vaccine

25
Q
Which of the following antibiotics is active at low redox potential?
A) linezolid 
B) tetracycline
C) metronidazole
D) Colistin
A

C) Metronidazole

26
Q
Beta-lactams inhibit the synthesis of which of the following?
A) cell membrane 
B) cell wall
C) bacterial ribosomes 
D) protein synthesis
A

B) cell wall