Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Final Exams - 2nd year > 2015 biochem > Flashcards

2015 biochem Flashcards

1
Q

What is the change that occurs in prion disease?
A. Increased beta sheets
B. Increased alpha helices

A

A. Increased beta sheets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
Which structure level is altered in prion disease? 
A. Primary
B. Secondary 
C. Tertiary
D. Quaternary
A

B. Secondary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The deletion of Phe508 in cystic fibrosis affects what?

A

The ATP binding domain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A protein was mutated to lack a signal peptide. What can be assumed about this protein?

A

It was synthesized on free ribosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q 
An antibiotic blocks the 30s ribosomal subunit. Which part of the translation will be affected?
A. Elongation 
B. Initiation
C. Translocation 
D. Termination
A

A. Elongation

I think its B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

An antibiotic that inhibits translocation results in a peptide that’s
A. Shorter
B. Longer

A

A. Shorter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Citrate was exported from the mitochondria into the cytosol. What will this transport stimulate?
A. Lipogenesis
B. Glycolysis
C. Lipolysis

A

A. Lipogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which transporter in the electron transport chain can carry two electrons and donate one at a time?
A. Coenzyme Q
B. Cytochrome C

A

A. Coenzyme Q

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which enzyme is targeted in treating gout?

A

Xanthine Oxidase (which makes uric acid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the effect of prolonged trans-fat consumption?
A. Suppressing the activity of LDL receptors
B. Increasing the activity of LDL receptors
C. Higher HDL levels

A

A. Suppressing the activity of LDL receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
What is the principal product of glycogen breakdown in muscles? 
A. Glucose
B. UDP-Glucose
C. Glucose-1-phosphate 
D. Maltose
A

C. Glucose-1-phosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What causes Alzheimer disease?
A. Increased beta sheets
B. Deoxygenated valine beta hemoglobin
C. Incorrect cleavage of Amyloid Protein Precursor

A

C. Incorrect cleavage of Amyloid Protein Precursor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which bond is not broken if a protein is cooked?
A. H-bond
B. Electrostatic bond
C. Peptide bond

A

C. Peptide bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does a deficiency in vitamin C impair?

A

Hydroxylation of proline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does an allosteric effector do?
A. Stabilize the protein configuration
B. Bind to the active site
C. Alters the stability of the protein through covalent modifications

A

A. Stabilize the protein configuration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q 
If we add 0.1 mM of a noncompetitive inhibitor to a sample where the Kmwas 0.5 and Vmax was 20, what is correct regarding km and Vmax after this whole process?
A. vmax = 20, km = 5 
B. vmax = 10, km = 0.5 
C. vmax = 30, km = 2.5 
D. vmax = 20, km = 0.5
A

B. vmax = 10, km = 0.5

17
Q 
Which lipase requires a colipase to function? 
A. Pancreatic lipase
B. Phospholipase C 
C. Hepatolipase
D. Hormone sensitive lipase
A

A. Pancreatic lipase

18
Q 
Which of the following is the product of the rate-limiting step of cholesterol synthesis?
A. Acetoacetyl coA 
B. HMG CoA
C. Mevalonic acid 
D. IPP
A

C. Mevalonic acid

19
Q 
Where in a cell, do desaturase reactions take place? 
A. Golgi Apparatus
B. Mitochondria 
C. Nucleus
D. Endoplasmic Reticulum
A

D. Endoplasmic Reticulum

20
Q 
What causes acidosis in prolonged starvation? 
A. Ketone bodies
B. Acetone
C. Gluconeogenesis 
D. Fatty acid oxidation
A

A. Ketone bodies

21
Q

In what way does the pentose phosphate pathway aid antioxidants?
A. Converts ribulose-5-P to ribose5-5-phosphate
B. Keeps glutathione in a reduced state

A

B. Keeps glutathione in a reduced state

22
Q

Which of the following drives the movement of H from the matrix into the intermembrane space? (diagram)
A. Concentration gradient
B. Electrochemical gradient
C. ATP hydrolysis
D. Energy of the redox reactions from ETC

A

D. Energy of the redox reactions from ETC

23
Q

Philadelphia chromosome is associated with which caner?

A

Chronic Myeloid Leukaemia

24
Q

What is the function of a deacetylation reaction?

A

reduces gene expression.

25
Q

What is the function of a deacetylation reaction?

A

reduces gene expression

26
Q

Which of the following is a spontaneous cause for DNA mutation?
A. Tautomerization
B. UV irradiation
C. Metabolism that produces ROS

A

A. Tautomerization

27
Q

What reaction is catalyzed by superoxide dismutase?

A

O2 + 02 -> h2O2

28
Q

Which of the following should a patient with carnitine 1 deficiency avoid?
A. Long chain fatty acids
B. FA<12C

A

A. Long chain fatty acids

29
Q

What does a-amantin inhibit?
A. RNA polymerase II
B. RNA polymerase I
C. RNA polymerase III

A

A. RNA polymerase II

30
Q

Which of the following contains a primase?
A. DNA polymerase B
B. DNA Polymerase alpha
C. DNA Polymerase Y

A

B. DNA Polymerase alpha

31
Q

What is the annealing temperature for this DNA sequence:

5-ACA CAG ATA CAG ATA GCT-3

A

2(#A and T) + 4(# C and G)= 2 X 11 + 4X7= 50C

32
Q

Diagram of fructose pathway in glycolysis. What action of fructose can potentially cause liver damage?
A. lack of regulation by phosphofructokinase1
B. Aldolase B deficiency
C. DHAP accumulation

A

A. lack of regulation by phosphofructokinase1

33
Q

Which of the following enzymes is affected by Nag?

A

Carbamyl synthase

34
Q 
Which of the following is a source for ammonia in the urea cycle? 
A. Aspartate
B. Glutamine
C. Glatamate
D. Alanine
A

B. Glutamine

Final Exams - 2nd year (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions