2014 biochem Flashcards
What drives the pumping of H? (matrix -> intermembrane space): A) Energy of redox reaction B) Concentration gradient C) Electrochemical gradient D) ATP hydrolysis
A) Energy of redox reaction
what is true about the digestive process?
Pepsinogen activated autocatalysis
Which enzyme provide proof-reading in translation? A) Amino acid hydrolase B) tRNA transferase C) aa tRNA synthetase D) Peptidyl transferase
C) aa tRNA synthetase
What is (what is a characteristic of Satellite DNA? A) Non coding transposons B) Non coding retrotransposons C) Non coding tandem repeats D) Non coding introns
C) Non coding tandem repeats
Which of the following will be lacking in collagen if there is a Cu deficiency? A) Cross bridges B) Hydroxylation C) S-S bonds D) Hydrogen bonds
A) Cross bridges
What is true about Transaminases?
A) They have pyridoxal phosphate as a cofactor
B) They are not reversible
C) They are not specific
A) They have pyridoxal phosphate as a cofactor
Which of the following is involved in B-turns? A) Proline B) Glycine C) Lysine D) Glutamate
A) Proline
Which of the following is true about glucagon? A) Increase glucose uptake by cells B) decrease glucose synthesis C) Increase glucose synthesis D) Increase protein synthesis
C) Increase glucose synthesis
What is the use of a microarray chip?
A) detecting misfolded proteins
B) gene expression profile
B) gene expression profile
What is the cause of Alzheimer’s disease?
Abnormal protein processing
What is associated with the inversion in the HEMA gene? A) Severe hemophilia A B) Mild hemophilia A C) Severe hemophilia B D) Blood clotting disorder
A) Severe hemophilia A
What is used for mRNA 5'capping? A) GMP B) CMP C) AMP D) UMP
A) GMP
What best describes fatty acid synthase?
A) one enzyme molecule contains 6 enzymes and 1 protein
B) can synthesize a fatty acid molecule with a length up to 18C units
C) Forms antiparallel dimer to function
C) Forms antiparallel dimer to function
Which of the following is mainly used as energy for gluconeogenesis in the liver?
A) Proteins
B) glycerol
C) Fatty acids
C) Fatty acids
What happens after a meal during short period starvation (4-12 hours) to maintain the blood glucose levels?
A) glycogen breakdown
B) gluconeogenesis
C) lipolysis
A) glycogen breakdown
What is the purpose of the glucose alanine cycle?
A) Eliminate nitrogen from the muscles
B) Decrease ammonia excretion by the liver
A) Eliminate nitrogen from the muscles
What is the product of non-oxidative stage of Pentose phosphate pathway?
A) glucose 6-phosphate
B) ribose-5-phosphate
C) NADPH
B) ribose-5-phosphate
What’s a characteristic of trans fat?
A) can only be produced artificially but not naturally
B) can be produced in our body in beta-oxidation
B) can be produced in our body in beta-oxidation
What is the substrate for glycogen synthase?
UDP-glucose
which of the following is a main product of catabolism?
A) NAD+
B) NADH
C) NADP+
B) NADH
a patient suffers from glycogen storage disease type Ia (Von Gierke disease). This disease can result from a deficiency in glucose 6-phosphatase. What is the patient most likely going to suffer?
A) hypoglycemia
B) normal growth
C) normal blood sugar levels
A) hypoglycemia
What is a characteristic of cooperativity in enzymes?
has more than one catalytic site
what is the Consequence of high Vmax of glucokinase?
A) To allow rapid uptake of glucose by the liver after a meal
B) Preventing hypoglycemia
C) Rapid synthesis of glucose when it’s levels are low
D) rapid release of glucose cuz it will have higher capacity
A) To allow rapid uptake of glucose by the liver after a meal
The signal peptide of a lysosomal protein was cleaved in the ER, where will the protein go? A) lysosome B) secretion C) nucleus D) Golgi
A) lysosome
What is a characteristic of DNA euchromatin?
A) actively transcribed
B) highly acetylated
C) highly methylated
A) actively transcribed
Why can’t we detect the template DNA in PCR?
it remains unamplified
Which of the following processes tRNA?
RNase p
Which of the following is removed from the exterior of the cytoplasmic membrane by floppase (flippase)?
A) Phosphatidylserine
B) phosphatidylcholine
A) Phosphatidylserine
what fat substitute is not digested in our body?
olestra (a fat substitute that adds no fat, calories, or cholesterol to products)
What are the restriction enzymes?
A) They protect the bacteria as they cut the foreign DNA
B) They cut the bacterial DNA because it is methylated
C. They cut the viral DNA because it is methylated
A) They protect the bacteria as they cut the foreign DNA
which of the following affects the annealing temperature?
the primer length and sequence
