1F - Obstetric Anesthesia Flashcards
What are hematologically increased in a pregnant woman?
plasma volume, blood cell volume, procoagulant factors
Hgb and hematocrit during pregnancy is decreased or increased?
Decreased
What ASA class is a pregnant patient?
Class 2 with mild systemic disease
Serum cholinesterase activity in pregnant women is decreased by?
20%
Total protein in preg woman is?
Increased
plasma protein in preg woman is?
De
to below 6g/dL
Free drugs in preg woman are?
In
What are de in cardio in preg woman?
SVR, arterial bp
what are in in cardio in preg woman?
HR, CO, SV
*inc in SVR greater than inc in CO
Supine hypotension syndrome is caused by the occlusion of what greater vessel?
Superior vena cava
What maneuver can help alleviate supine hypotension syndrome?
Left uterine displacement using a wedge under the hip and left lateral decubitus position
The diaphragm during pregnancy is displaced where?
Cephalad
what partial pressure is decreased in the blood during pregnancy?
CO2 pressure
Due to inc metabolic rate and dec FRC, what is the preg woman presidposed to?
Hpoxemia
Overall GI transit time during preg is?
Increased
*gastric emptying time is not prolonged
What GI function is distorted and incompetent during pregnancy?
LES
Before any surgical procedure, due to the changes in GI tract during pregnancy, what drugs are given?
H2 blockers and metoclopramide
The preg patient requires more or less inhaled anesth?
Less
What categories in ficks principle permits placental transfer of drugs?
Non ionized, lipid soluble and small molecular size (<500Da)
What vasoconstrictor is used to prevent transfer of drugs to the fetus?
Epinephrine (vasoconstrictor)
What drug if induction to to delivery exceeds 5-10 minutes, causes newborn depression?
Nitrous oxide (NO)
Metabolic clearance of the fetus when compared to an adult is inc, dec, or same?
Same
renal clearance of fetus when comparesd to an adult is inc, dec, or same?
inc
The spinal cord segments involved in labor pains at the first stage of labor are?
T10 to L1
Spinal cord segments involved in the second stage labor pains?
S2 to S4
Most commonly administered for labor analgesia?
Opioids
what is the go to drug for analgesia?
Meperidine
IV effects in 5-10 mins
IM peaks in 40-50 mins
what type on obstetric analgesia has lower incidence of nausea and vomiting and dysphoria?
Antagonist-agonist - nalbuphine, butorphanol
safer then meperidine - ceiling effect on ventilatory depression
Synthetic opioids upon repeated doses can cause what fetal complication?
neonatal depression
*fentanyl
Which potent analgesic causes amnesia?
Ketamine
What stage of labor does regional anesth prolong?
None
What epidural anesth are called walking epidural by sparing of motor skills?
Ropivacaine and Bupivacaine
What form of regional anseth is used for imminent deliveries or multiparous deliveries?
Spinal anesth
fentanyl + bupicavaine
Repeated spinal anesth can cause what problem to the patient?
postdural puncture headache
the painting wall sites of defence requires giving medications in what order of spaces?
Spinal then epidural
If patients have aortic stenosis what form of analgesic should be given?>
Opioid only
What is the ideal analgesic technique for labor?
Combined spinal and epidural anesth
*opioid only or opioid + bupivacaine
If central neuraxial anesthetic technique is contraindicated, what is the alternative?
Paravertebral lumbar sympathetic block
What nerve block is used for forceps delivery and episiotomy?
Pudendal nerve block
What is the most often used is the most often used inhalational anesthesia?
Nitrous oxide
What is the most common complication of neuraxial anesth?
Hypotension
Interval of monitoring in patients receiving neuraxial anesth?
Every 2-3 mins for first 20 mins
Drug and method used for neuraxial anesth?
Morphine either epidural or intracthecal
What dermatome is blocked for surgery of the preg woman?
T4
What form of anesth is most commonly used in CS delivery?
Spinal anesth
In addition to bupivacaine used in spinal anesth for CS delivery, what is added to increase rapidity of the blockade, and reduce symptoms such as nausea and vomiting and shivering?
Opioids
What is the main disadvantage of lumbar epidural anesth?
Slow onset
Bupivacaine is associated with greater risk of what complication?
LAST (local anesth systemic toxicity)
What combination drug for lumbar epidural anesth poses less risk of LAST compared to bupivacaine?
Ropivacaine + fentanyl
What is used when there is absolute or relative contraindications for neuraxial anesth?
general anesth
What evaluation is important before undergoing general anesth?
preoperative airway evaluation
What is the leading cause of maternal death related to anesth?
inability to intubate or ventilate
What preventive measure to hypoxia is done before induction of general anesth?
denitrogenization for 3-5 minutes or 4 deep breaths of 100% oxygen
what muscle relaxant is used to facilitate intubation?
Succinylcholine
Which form of anesth is more related to anesth related maternal deaths, general or neuraxial?
General anesth
Treatment for hypotension syndrome caused by anesth?
Vasopressin, epinephrine, Left uterine displacement, co load etc
Treatment for convulsions occurring in LAST?
benzodiazepines
Treatment for ventricular arrhythmias in LAST?
Amiodarone
If unresponsive to lipid emulsion, what is the treatment?
Cardiopulmonary bypass
withdrawal of what hormone causes post puncture headache?
estrogen
Most commonly abused substance?
Tobacco