Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

PGI > 1.7.2013(pathology) 54 > Flashcards

1.7.2013(pathology) 54 Flashcards

0
Q

Schilling test stages

A
  1. Radioactive B12
  2. along with IF
  3. after antibiotic treatment
  4. after giving pancreatic enzymes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

False positive D Xylose test

A 
Bacterial overgrowth
Diarrhoea
Delayed gastric emptying
Renal insufficiency 
Vomiting 
Ascitis/pleural effusion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tests in steatorhea

A

D Xylose

Small intestinal biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q 
D Xylose test in 
Chronic pancreatitis
Bacterial overgrowth
Celiac disease
Illeal disease
Intestinal lymphangiectasia
A

Normal in all except celiac disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Schilling test in celiac disease

A

Normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Celiac disease affects

A

Duodenum

Proximal jejunum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Intestinal stagnant loop syndromes

A

Jejunal diverticulosis
Stricture
Ileocolic fistula
Anatomic blind loop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Inflammatory causes of folate deficiency

A

TB
psoriasis
Exfoliative dermatitis
Malaria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Excessive urinary loss of folate is seen in

A

CCF

active liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Anti folate drugs

A

Nitrofurantoin

Tetracycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Non neoplastic causes of elevated CEA

A

Smoking
IBD
pancreatitis
Hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

LDH is tumor marker for

A

Ewing

Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

CA 19-9 is elevated in

A

Colon Ca
Pancreatic Ca
Breast Ca

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

MHC which is a component of hormone receptor

A

MHC1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Medium to select for hybridoma cells

A 
HAT medium
  Hypoxanthine
  Aminopterin
  Thymidine
HAT medium inhibits denovo purine synthesis pathway
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Characteristic of myeloma cells

A

Immortal

HGPRTase -ve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hybridoma technique was developed by

A

Kohler and milstein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Cell fusion in hybridoma technique is brought about by

A

PEG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Popcorn classification

A

Pulmonary hamartoma
Mediastinal lymph node in Acute histoplasmosis
Degenerated fibroadenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Most common site of pulmonary hamartoma

A

Peripheral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Most common benign tumor of lung

A

Pulmonary hamartoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Specific CT finding in pulmonary hamartoma

A

Fat and calcification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

p14 ARF increases p53 activity by

A

Inhibiting MDM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Most common type of Hodgkin lymphoma

A

Nodular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Nodular Hodgkin lymphoma cells,CD
CD15 and CD30 +ve | CD45 and CD20 -ve
25
Nodular sclerosis is common in
Both male and female
26
Most EBV +ve Hodgkin
Lymphocyte depleted (poor prognosis)
27
Reed sternberg cells in lymphocyte depleted type
Reticular
28
Reed sternberg cells in lymphocyte predominant type
L and H/popcorn cells
29
Hodgkin subtype with CD15 and CD30 negativity
Lymphocyte predominance(it is CD20+ve)
30
Cancers associated with asbestosis
Ca lung and bronchus(SCC or adenocarcinoma) Pleural or peritoneal mesothelioma Colon cancer Laryngeal carcinoma
31
Inherited Hypercoagulable states
``` DYSFIBRINOGENEMIA Leiden Prothrombin mutation Protein C and S deficiency Antithrombin III deficiency ```
32
Conditions associated with low complement levels
Idiopathic proliferative glomerulonephritis Cryoglobulinemia Shunt nephritis Atheroembolic renal disease
33
Glomerulonephritis with normal complement
HSP | IgA nephropathy
34
Celiac disease biopsy appearance
Flat Villous atrophy,crypt hyperplasia Overall mucosal thickness remains the same
35
SLE lesions in kidney
``` Class 1: minimal mesangial Class 2: mesangial proliferative Class 3: focal proliferative Class 4:diffuse proliferative(wire loop) Class 5: membranous(sub epithelial,all others have Subendothelial deposits) Class 6: sclerotic nephritis ```
36
Type 2 RPGN
``` PSGN IgA nephropathy HSP SLE MPGN cryoglobulinemia ```
37
MHC 1 is associated with which hormone receptor
LH
38
Granulovacuolar degeneration is seen in
Alzheimer's disease
39
Good prognostic factor in neuroblastoma,CD
CD44
40
DNA ploidy,poor prognosis in neuroblastoma
Diploid Near diploid Near tetraploid
41
Serum biochemical markers of neuroblastoma
LDH ferritin Poor prognosis if elevated
42
Amyloid deposition in FMF
AA
43
Most common cause of secondary amyloidosis
Rheumatoid arthritis
44
Tumors associated with secondary amyloidosis
Renal cell carcinoma | Hodgkin
45
Heat test for bence jones protein
Precipitate at 50-60 C | Redissolve at 100 C
46
Paragangliomas are chromaffin
Positive
47
TLR 4 binds to
LPS(Gram negative bacteria) | HSF60(chlamydia)
48
TLR that binds to flagellin
TLR 5
49
TLR 6 binds to
CpG DNA
50
TLR3 binds to
Double stranded RNA(viruses)
51
TLR 2 binds to
``` Lipoproteins Peptidoglycan(GPB) LPS of leptospira Lipoarabinomannan and phosphatidyl inositol dimannoside of mycobacteria GPI anchor(trypanosomes) Zymosan(fungi) ```
52
TLR belongs to _____ family
IL-1 receptor family
53
Basophilic Dyskeratosis is seen in
Darier disease
54
Dyskeratosis
Abnormal keratinisation occurring prematurely in cells below stratum granulosum layer
55
Chondrocalcinosis
``` Calcium pyrophosphate deposition disease Acromegaly Hyperparathyroidism Alkaptonuria Gout Wilson disease ```
56
Intervertebral disc calcification,causes
``` Alkaptonuria Gout CPPD DISH AS degenerative spondylosis Hemochromatosis ```
57
Cause of metastatic calcification
Elevated Ca phosphate product(more than 60-70) | With normal ca phosphate product but after renal transplant
58
PSGN develops how many weeks after pharyngitis and impetigo
1-3wks after pharyngitis | 2-6wks after impetigo
59
Nephritogenic streptococcal strains
Impetigo 2,47,49,55,57,60 Pharyngitis 1,2,3,4,12,25,49
60
Causes of decreased osmotic fragility
``` Sickle cell Anemia Thalassemia Iron deficiency Anemia Reticulocytosis Post splenectomy ```
61
Causes of Anemia in CRF
``` Decreased erythropoietin Decreased RBC survival Bleeding diathesis Iron deficiency Hyperparathyroidism/bone marrow fibrosis Chronic inflammation Folate or B12 deficiency Hemoglobinopathy Comorbid conditions ```
62
Megaloblastic Anemia refractory to folate/B12 therapy
Orotic aciduria Thiamine responsive Anti metabolites Myelodysplasia/some cases of AML
63
Worms causing iron deficiency Anemia
Hook worm Shistosoma Trichuris
64
Changes in primary TB
``` Ghon complex Pleural effusion Calcification Cavitation Fibrosis Milliary ```
65
Common causes of malignant pleural effusion
Lung Breast Lymphoma
66
Drug induced pleural effucsion
Methysergide Procarbazine BAND
67
Causes of transudate pleural effusion
``` CCF nephrotic syndrome Cirrhosis Pulmonary embolism Peritoneal dialysis SVC obstruction Myxedema Urinothorax ```
68
Side of pleural effusion in CCF
Right | Same in cirrhosis

PGI (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions