16. Breast Pathoma Flashcards
What are the lobules and ducts lined by in the breast?
luminal cell layer
myoepithelial cell layer (contractile function)
Acute Mastitis
which organism causes this
Staph Aureus.
infection of the duct, purulent discharge
Fat necrosis
what does the biopsy show?
benign lump due to injury to breast tissue
necrotic fat with calcifications and giant cells
Fibrocystic changes
most common in premenopausal women
lumpy breasts, Blue dome cysts
whats Sclerosing adenosis
fibrosis of the acini and stroma of the breast
associated with calcifications
Intraductal papilloma
most common cause of _________
papillary= long like finger pertrusion in the lactiferous duct
most common cause of BLOODY NIPPLE
Fibroadenoma
estrogen sensitive?
Most common tumor in premenopausal females
tumor of fibrous tissue and glands
well circumscribed, mobile, marble like
-yes
Phyllodes Tumor
benign breast tumor with Leaf like lobulations
Ductal carcinoma in Situ (breast)
how is it detected on mammography
whats the comedo subtype
Malignant proliferation of cells in ducts
- No invasion* into the basement membrane
- micro calcifications
-Comedo:high grade cells w/ necrosis and dystrophic calcification in center
Paget’s dz of the breast/nipple
how does it present?
DCIS that extends to the nipple
-nipple ulceration/erythema
Invasive ductal Carcinoma (breast)’
advanced tumors can cause ____
forms rock-hard“duct like” structures
-dimpling of skin / retraction of nipple
Inflammatory breast cancer
what does the breast look like?
prognosis
Cancer of the Dermal lymphatics
Peau d’orange (breast dimples like orange skin)
Large boob
pretty bad prognosis
Invasive lobular carcinoma
how does it look?
Orderly row (Indian file) of cells due to decr. E-cadherin
