104 Poisoning

Question 1

Give an example of some benzodiazepines

Answer 1

Carbamazepine, Diazepam, Midazolam

Question 2

What is the antidote to benzoiazepine poisoning and what is the risk?

Answer 2

Flumazenil - resedation ones it wears off

Question 3

Name some tricyclic antidepressants and what is the antidote?

Answer 3

Amitriptylline, butriptilline and methylphenidate - no antidotes

Question 4

What are the signs of OD with TCA’s?

Answer 4

Large pupils, coma, hypothermia, arrythmias and hypotension

Question 5

What are the OD signs with benzodiazepines?

Answer 5

drowsiness, coma, ataxia

Question 6

How might a patient who has OD’d on paracetemol present?

Answer 6

Abdominal pain, bruising and blood glucose changes (hypo/hyper)

Question 7

What is the treatment for paracetemol OD?

Answer 7

Activated charcoal within the hour or N-acetyl cysteine

Question 8

What is n-acetyl-cysteine?

Answer 8

A glutathione precursor

Question 9

What is the antidote for opioid poisoning?

Answer 9

Naloxone

Question 10

What are the signs of opioid OD?

Answer 10

small pupils, bradypnoea, coma

Question 11

What is the antidote for beta blocker OD?

Answer 11

Glucagon

Question 12

What are the signs of beta blocker OD?

Answer 12

bradycardia

Question 13

What is alkaline diuresis used for?

Answer 13

treat aspirin poisoning - works well on weak acid, renally excreted drugs