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Pharmakologie > ZNS- Psychopharmaka > Flashcards

ZNS- Psychopharmaka Flashcards

1
Q

Tranquillantien/ Anxiolytika

A

Kurz wirkende Benzodiazepine (< 6 h):

  • Triazolam
  • Midazolam

Mittellang wirkende Benzodiazepine (6-24 h):

  • Lorazepam (anxiolytisch)
  • Oxazepam

Lang wirkende Benzodiazepine (> 24 h):

  • Diazepam
  • Flunitrazepam (sedierend, hypnotisch)
  • Tetrazepam (v.a. als Myotonolytikum; s. Muskelrelaxantien)
  • Clonazepam (antikonvulsiv)
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2
Q

Benzodiazepin- Antagonisten

A

-Flumazenil

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3
Q

Atypische Anxiolytika

A
  • Buspiron (5HT1A- Agonist)
    (s. Arzneistoffe mit Wirkung auf serotoninerge Systeme)
  • Zolpidem (höhere Affinität zur alpha1 UE des GABA- A Rezeptors, insb. Sedation)
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4
Q

Konventionelle Neuroleptika

A

niederpotent: Levomepromazin
mittelpotent: Perazin, Chlorpromazin
hochpotent: Haloperidol, Fluphenazin

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5
Q

„„Atypische““ Neuroleptika

A
  • Olanzapin, Clozapin (5HT2A-, D2- und D4- Antagonist, M4- Agonist)
  • Risperidon (5HT2A- D2- Antagonist, 5HT1A Agonist, Wiederaufnahmehemmung von NA und 5HT)
  • Amisulprid (D2- und D3 Antagonist, niedrige Dosis Wiederaufnahmehemmung)
  • Aripiprazol (voller Antagonist an 5HT2A, partieller Agonist an 5HT1A, D2)
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6
Q

Antidepressiva

-Selektive Serotonin-Rückaufnahme-Inhibitoren (SSRI)

A

-Sertralin

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7
Q

Antidepressiva

-Selektive Serotonin- und Noradrenalin-Rückaufnahme Inhibitoren (SSNRI)

A

-Venlafaxin

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8
Q

Antidepressiva

Nicht-selektive Monoamin-Rückaufnahme-Inhibitoren (NSMRI): Trizyklische Antidepressiva

A
  • Amitriptylin
  • Clamipromin
  • Desipromin
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9
Q

Antidepressiva

Noradrenalin-Dopamin-Rückaufnahme-Inhibitor (NDRI)

A

-Bupropion

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10
Q

Antidepressiva

alpha2-Rezeptorantagonist

A

-Mirtazapin

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11
Q

Antidepressiva

MAO-Hemmstoff

A
  • Tranylcypromin

- Moclobemid

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12
Q

Antidepressiva

-Pflanzliches Antidepressivum:

A

-Johanniskraut

Hyperforin, Hypericin, Cytochrom P450 Ind.

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13
Q

Stimmungsstabilisatoren

A

-Lithium

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14
Q

Zentral stimulierende Wirkstoffe

Psychoanaleptika

A
  • Amphetamin (historisch)
  • Analoga
    (z. B. 3,4- Methylendioxymethamphetamin (MDMA, Ecstasy)
    (s. Arzneistoffe mit Wirkung auf das sympathische NS)
  • Methylphenidat
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15
Q

Zentral stimulierende Wirkstoffe

Xanthinderivate

A
  • Theophyllin (Asthmamittel)

- Coffein

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Pharmakologie (49 decks)

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