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Pharmakologie > Tuberculostatika > Flashcards

Tuberculostatika Flashcards

1
Q

frisches Granulom

A
  • Rifampicin, Isoniazid

- Ethambutol, Pyrazinamid

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2
Q

käsig verändertes Tuberkulom

A

-Rifampicin, Isoniazid

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3
Q

Offene Kaverne

A
  • Rifampicin, Isoniazid

- Ethambutol, Streptomycin

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4
Q

Streptomycin

A
  • nur bei offener Tuberkulose
  • auch atypische M.
  • Aminoglykosid
  • parenteral (alle anderen oral)
  • UEW: ototixisch, nephrotoxisch
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5
Q

Rifampicin

A
  • in allen Krankheitsstadien aktiv

- auch M. leprae und atypische M.

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6
Q

Isoniazid (INH) und Pyrazinamid (PZA)

A
  • hemmen Synthese von NS und Mykolsäuren der Tuberkelbakterien
  • niedrige Konz: bakteriostatisch
  • hohe Konz.: bakterizid
  • UEW: ZNS, GIT, Alkoholintoleranz (Met. Leber)
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7
Q

Ethambutol (EMB)

A

-gut gewebsgängig
-bakteriostatisch auf schnell wachsende Keime
(alle anderen bakterizid)
-synergistisch mi INH und RMP
-auch atypische Mykobakteriose
-UEW: Schädigung des N.opticus

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Pharmakologie (49 decks)

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