Z 331 final Flashcards
motor unit
motor neuron and all the muscle fibers it supplies;
fibers spread throughout muscle;
contract asynchronously to prevent fatigue
muscle twitch
motor unit’s response to single action potential of motor neuron; simplest contraction observable in lab
3 phases of muscle twitch
latent: events of excitation-contraction coupling, no muscle tension
period of contraction
period of relaxation: tension declines to zero
graded muscle responses
contractions are smooth and vary in strength depending on demands
2 ways muscle contractions can be graded
changing frequency of stimulation, changing strength of stimulation
wave (temporal) summation
result of increase frequency of stimulation; muscle doesn’t completely relax between stimuli; second contraction of greater force; main function is smooth contractions
unfused (incomplete) tetanus
result of wave summation
fused (complete) tetanus
muscle reaches maximum tension, from very quick stimuli; no muscle relation, muscle fatigue
recruitment
multiple motor unit summation (from increased strenth of stimulus), controls force of contraction
size principle
motor units with smallest fibers recruited first, larger fibers recruited as stimulus intensity increases
isometric contraction
no shortening, tension increases but does not exceed load, cross bridges generate force but do not move actin filametns
isotonic contraction
muscle shortens, tension exceeds load
concentric contraction
muscle shortens and does work
eccentric contraction
muscle generates forces as it lengthens
muscle tone
constant slightly contracted state of all muscles, due to spinal reflexes
spinal reflexes
groups of motor units alternately activated in response to input from stretch receptors in muscles, responsible for muscle tone
force of muscle contraction depends on
number of myosin cross bridges attached.
- number of muscle fibers stimulated
- relative size of fibers
- frequency of stimulation
- degree of muscle stretch
the only energy source for contractile activities
ATP
3 ways ATP can be regenerated
direct phosphorylation of ADP by creatine phosphate
anaerobic glycolysis (glucose to lactic acid)
aerobic respiration
muscles store enough ATP to
start contraction
creatine kinase
catalyzes creatine phosphate + ADP –> creatine + ATP
creatine phosphate provides maximum muscle power for ? seconds
~15
where does CP come from?
some made from ATP at rest (reversible reaction with creatine phosphokinase), some stored in muscle
more pyruvate than mitochondria can use results in
lactic acid production from anaerobic pathway
aerobic respiration equations
glucose + oxygen –> carbon dioxide + water + ATP
aerobic respiration substrates can be
glucose (pyruvic acid), amino acids, or fatty acids
anaerobic threshold
point at which muscle metabolism converts to anaerobic glycolysis
muscle fatigue
inability to contract even though muscle may stil be receiving stimuli
causes of fatigue
ATP/CP shortage, depletion of metabolic reserves, damage to sarcolemma and SR, low pH (lactic acid) inhibits enzymes and effects CNS, motor nerve fibers deplete Ach, unable to release Ca, muscle exhaustion and pain
excess post-exercise oxygen consumption (EPOC)
extra oxygen the body must take in for restorative processes, difference between amount of oxygen needed for total aerobic activity and amount actually used
slow oxidative fibers
high endurance, aerobic metabolism, smaller, more mitochondria, little power, high blood supply, contain myoglobin, red
fast glycolytic fibers
quick, no oxygen, large, few mitochondria, large glycogen reserves, strong, fatigue quickly, little myoglobin, white
fast oxidative (intermediate) fibers
mid sized, intermediate power, contract quickly, oxygen dependent, some myoglobin, more capillaries than fast
muscle fibers of a motor unit are
same type