Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

B&M Exam 2 > Yersinia > Flashcards

Yersinia Flashcards

1
Q

important species

A

y pestis – black plague
y enterocolitica
y pseudotuberculosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

gram
shape
staining
lactose fermenter?
urease
coagulase
oxidase
TSI

A

gram negative
rod
bipolar staining
lactose non fermenter
urease positive
coagulase positive
oxidase negative
no gas on TSI, but still changes color to yellow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

motility?

A

flagella – y enterocolitica and y pseudotuberculosis
no flagella – y pestis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

is this a bioterrorism agent

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how is y pestis spread

A

flea bites
meat ingestion of infected rodents
contact with infected secretions or tissues
aerosol transmission of pneumonic plague

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

y pestis and the plague

A

causes bubonic plague – gangrene of toes turns dead digits black (black death)
can also infect lungs (pneumonic plague) – cough up dark black blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

antigen serotypes

A

y pestis – antigenically homogenous
y enterocolitica – 70 O antigen serotypes
y pseudotuberculosis – 15 O antigen serotypes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which yersinia can proliferate at refridgerator temperatures

A

y enterocolitica

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

habitat

A

gastrointestinal tract of animals
arthropods – y pestis and fleas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

is this primarily an animal pathogen

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how many plasmids

A

3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

surface structures

A

capsule – serum resistance
LPS
low calcium response virulence (LcrV)
attachment invasion (Ail)
yersinia adhesion (Yad)
invasin protein A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

enzymes

A

plasminogen activator (Pla) – protease
global stress requirment (Gsr) – protease
coagulase
yersinia murine toxin (Ymt) – phospholipase D
urease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

toxins

A

T3SS
yersinia outer protein (Yops)
yersinia stable toxin (Yst)
iron robbing/acquisition – siderophores, yersinibactin, hemin storage proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the most important enzyme of yersinia

A

protease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what doe global stress requirement do

A

intracytopalsmic survival within macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what does yersinia murine toxin do

A

protect yersinia within fleas by forming capsule

18
Q

how does yersinia get to mesenteric lymph nodes

A

hangs out in macrophages or M cells
moves into peyer’s patches
microcolonies and replication
then get to mesenteric lymph nodes
microcolonies and replication

19
Q

y pestis transmission

A

flea borne
air borne
amoeba
vertebrates

20
Q

what does bubonic plague infect

A

lymph nodes – swollen and painful

21
Q

what does pneumonic plague

A

lungs
spread (airborne) to others
no longer need fleas for transmission

22
Q

what is the primary reservoir of y pestis

A

commensal flea-rodent cycle

23
Q

initial transmission of y pestis results in what

A

bubonic plague

24
Q

bacteremia of y pestis results in what

A

infection of lungs – pneumonic plague

25
Q

does pneumonic plague need fleas for transmission

A

no – airborne

26
Q

what animals are not susceptible to clinical plague, what are the exceptions

A

ruminants, equine, pigs not susceptible
camels and goats are susceptible

27
Q

how is y pestis transmitted from flea to rodent

A

grows in midgut of flea
flea draws viable y pestis into esophagus during feeding
bacteria multiply and block proventriculus
force flea to regurgitate infected blood onto host when it tries to swallow

28
Q

bubonic form of y pestis

A

lymph node swelling
fever
headache

29
Q

penumonic form of y pestis

A

cough up bloody sputum
aerosol spreading

30
Q

septicemic form of y pestis

A

death

31
Q

transmission of y enterocolitica and y pseudotuberculosis

A

feco oral route
foodborne agent

32
Q

is y enterocolitica and y pseudotuberculosis zoonotic?

A

yes

33
Q

primary reservoir of y enterocolitica and y pseudotuberculosis

A

swine

34
Q

y enterocolitica symptoms

A

mesenteric lymphadenitis
terminal ileitis
acute gastroenteritis
septicemia

35
Q

y pseudotuberculosis symptoms

A

mesenteric lymphadenitis
diarrhea
dehydration
septicemia in immune weak animals

36
Q

what does disease always involve

A

lymph nodes

37
Q

can you culture it yourself?

A

no, send to certain lab or else right to jail

38
Q

treatment

A

antibiotics not generally recommended
most recover on own with rehydration
antibiotics for severe systemic cases

39
Q

why should you treat y pestis immediatly

A

already in the blood from flea bite

40
Q

control

A

monitor rodent populations
control fleas
quarantine
vaccination (not safe)

B&M Exam 2 (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions