Bartonella

Question 1

respiration
fastidious?
gram
shape
motility
facultative? intracellular?
opportunistic?

Answer 1

aerobic
fastidious
gram negative
coccobacilli
motile – lophotrichous flagella
facultative intracellular bacteria – hide in erythrocytes
opportunistic – bartonellosis

Question 2

what cells do they hide in

Answer 2

erythrocytes

Question 3

hosts
vectors

Answer 3

hosts – wild and domestic animals, particularly cats
vectors – arthropods, cat fleas

Question 4

b henselae
vectors
reservoir
diseases

Answer 4

cat fleas vectors
cat reservoirs
cat scratch disease, endocarditis, bacteremia

Question 5

b bacilliformis
vectors
reservoir
diseases

Answer 5

sand flies vectors
human reservoirs
carrion’s disease

Question 6

b quintana
vectors
reservoir
diseases

Answer 6

body lice vectors
humans reservoir
trench fever

Question 7

b koehlerae
vectors
reservoir
diseases

Answer 7

cat fleas vectors
cat reservoirs
endocarditis, bacteremia, tissue infections

Question 8

b clarridgeiae
vectors
reservoir
diseases

Answer 8

cat fleas vectors
cats reservoirs
endocarditis, bacteremia, tissue infections

Question 9

b vinsonii subspecies berkhoffii
vectors
reservoir
diseases

Answer 9

brown dog tick vectors
cats, foxes, coyotes, dogs reservoirs
endocarditis, bacteremia, tissue infections

Question 10

b bovie
vectors
reservoir
diseases

Answer 10

biting flies vectors
ruminant reservoirs
endocarditis

Question 11

do most cats get disease

Answer 11

most cats asymptomatic, subclinical bacteremia

Question 12

what disease can cats get, who susceptible

Answer 12

feline bartonellosis
kittens, stress, concurrent disease

Question 13

is it zoonotic

Answer 13

yes – cat scratch fever

Question 14

how is cat scratch fever transmitted

Answer 14

infected flea poop gets under cat claws from grooming
cat scratches someone
bacteria gets in scratch wound

Question 15

disease in immunocompetent people

Answer 15

local lymphadenopathy
endocarditis

Question 16

disease in immunocompromised people

Answer 16

bacillary angiomatosis
cutaneous lesions (IL-8)
every organ system affected

Question 17

general symptoms

Answer 17

fever
fatigue
loss of appetite
weight lodd

Question 18

virulence

Answer 18

multiple flagella
bartonella adhesion A (BadA)
filamentous hemagglutination
twr system – adhesion to erythrocyte
VirB/VirD4-T4SS
iaIAB proteins
hemolysin
intracellular pathogen of erythrocytes

Question 19

what is required for diagnostics

Answer 19

repeated testing or combination of tests

Question 20

what kind of media

Answer 20

blood enriched media

Question 21

diagnosis

Answer 21

warthin starry stain
PCR
ELISA
IFA
histology
radiographs

Question 22

why is serology (ELISA, IFA) not recommended in cats

Answer 22

false positive results

Question 23

treatment

Answer 23

usually not necessary
antibiotics take 4-6 weeks

Question 24

control

Answer 24

no vaccines
prevent cat scratches and bites
flea control