Actinobacillus equuli Flashcards
subspecies
equuli
haemolyticus
A equuli subspecies equuli – hosts
horses
pigs
A equuli subspecies equuli – locations
primarily in tonsils, intestinal tract, reproductive tract
A equuli subspecies equuli – diseases
sleepy foal disease (acute bacteremia)
what happens when sleepy foal disease becomes chronic
purulent nephritis
arthritis
A equuli subspecies equuli – growth
macconkey agar
non hemolytic
but still has RTC toxin
a equuli subspecies haemolyticus – hosts
horses
a equuli subspecies haemolyticus – location
primarily in respiratory tract
a equuli subspecies haemolyticus – hemolysis?
hemolytic (RTX toxin)
prevalence of a equuli subspecies haemolyticus
less common
what is sleepy foal disease
foal bacteremia
when is sleepy foal disease obtained
in utero or during birth
what can happen if coinfection with strongyloides vulgaris
aneurysms
parasitic thrombus and arteritis
less acute infection of sleepy foal disease
abscesses and lesions in kidneys and joints
what disease shows facial celulitis
sleepy foal disease
a equuli subspecies haemolyticus – age of horses affected
primarily adult disease
but can also case sleepy foal disease
a equuli subspecies haemolyticus – diseases
abortion
stillbirth
meningitis
respiratory disease
wound infections
bacteremia
arthritis
endocarditis
inflamed wounds
zoonotic?
yes
isolated from humans following horse bites
virulence
LPS (endotoxin)
adherence factors
RTC toxin (weak)
compromising factors
mare carrying bacteria in genital tract prior to delivery
stress
infection
climate
parasitism – strongyloides vulgaris
overtraining
bad weather
immunity
vaccination of mares – not commercially available
sanitation of birthing environment
maternal antibodies in colostrum
prebreeding culture screening may prevent it
what would vaccination of mares provide
passive immunity to foals
treatment
antibiotics
