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I2 > X-Linked Hyper IgM Syndrome (Defect in lymphocyte activation/fx) > Flashcards

X-Linked Hyper IgM Syndrome (Defect in lymphocyte activation/fx) Flashcards

1
Q

Genetic cause of X-Linked HyperIgM Syndrome?

A

Mutations in CD40L

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2
Q

What is the antibody-related result of mutations in the CD40L?

A

Class-switching. even if MHCII + Peptide and TCR is present, the CD40L isn’t promoting class-switching

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I2 (29 decks)

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