Bare lymphocyte Syndrome

Question 1

BAre lymphocyte 1

Answer 1

TAP mutation causing failure or MHC 1 presentation.

Question 2

Bare lymphocyte II

Answer 2

MHC II defect: class II trans-activator (CIITA), regulatory factor of the X box 5 (RFX5), RFX-associated protein (RFXAP) and RFX ankyrin repeats (RFXANK; also known as RFXB).