IgA deficiency Flashcards
1
Q
What is the prevalence of IgA deficiency?
A
1/500-1/700; it’s fairly common
2
Q
What clinical problems are associated with IgA deficiency?
A
Often there are no clinical problems that present
3
Q
What is the pathophysiology behind the deficient IgA?
A
unknown
4
Q
Even though clinical problems are not associated with IgA deficiency, what might be a clinical symptom of it?
A
Inflammatory bowel disease because IgA is associated with mucosal immunity. Without it, infections may persist in the gut mucosal
5
Q
What might be a good tx for IgA deficiency?
A
Antibiotics
6
Q
What would happen if you transfused a patient with a large bolus of IgA?
A
Autoimmunity against the foreign IgA so anaphylaxis
