Common Variable Immunodeficiency Flashcards
1
Q
Clinical serum levels for CVID?
A
reduced IgG, IgA, and IgM
2
Q
With reduced antibody presence, what does this imply for infections?
A
poor responses when infectious agents are present, and the infections will reoccur because memory b cell development is lacking
3
Q
What causes CVID?
A
90% cases unknown but 13 genes and in general the genes involved in B cell survival, maturation or activation