X-Linked agammaglobulinemia Flashcards
1
Q
Mutations in?
A
BTK (Xlinked)
2
Q
Which cells are affected in XLA?
A
Mature B cells
3
Q
What do we look for (high or low levels) in the serum?
A
Loss of Serum Ig’s
4
Q
What does potentially this produce?
A
Autoimmunity
5
Q
What is BTK used for?
A
B cell differentiation signaling.
6
Q
If it is X-linked, male or female affected?
A
Men
