Women Health Drugs

Question 1

The REV aromatase-inhib Anastrozole Use

Answer 1

ER Breast cancer

Question 2

Synthetic P4, Levonorgestrel 4 Uses and Dosage

Answer 2

Anti-conception, Ovarian cysts, endomet cancer, breast disease
- Oral Dose Twice daily

Question 3

In regards to Women Pharm

Exemestane MOA

Answer 3

Aromatase IRReversible inhbitor

Question 4

In regards to Women Pharm

Tamoxifen 2 MOA

Answer 4

BREAST E2-R Blocker, Endomet and Bone E2-R Partial Agonist!

Question 5

Tamoxifen Use

Answer 5

1st line ER Breast cancer tx and prevent

Question 6

“Commy” Clomiphene 2 MOA

Answer 6

Partial E2 Agonist to inhibit ALL E2 in body, boosts GnRH by relieving neg feedback

Question 7

Ulipristal Main use and Dosage

Answer 7

Morning After, Single dose within 5 days (120 hrs)

Question 8

Contraceptive Ethinyl estradiol 3 serious sFx

Answer 8

Venous Thromboemolitic disease, MI, Stroke

Question 9

In regards to Women Pharm

Ethinyl Estradiol MOA

Answer 9

Synth Estro Blocks FSH/LH Release

Question 10

In regards to Women Pharm

Anastrozole MOA

Answer 10

Aromatase competitive inhibitor (cyp19A1)

Question 11

What makes Raloxifene a special ER blocker?

Answer 11

Protects bone!

Question 12

P4 Contraceptive, Levonorgestrel 3 sFx

Answer 12

Venous Thromboemolitic disease, MI, Stroke

Question 13

Breast E2R blocker, Tamoxifen 3 sFx

Answer 13

Hot flashes, vag bleed, Endomet cancer (bc partial agonist)

Question 14

Exemestane and Anastrozole (Aromatase blockers) 3 sFx less than Tamox, 2 sfX more than Tamox

Answer 14

Hot flash, Vag bleed, Endomet Cancer (less than Tamoxifen); Arthralgias, Vag Dryness (more than tamoxifen)

Question 15

Levonorgestrel MOA

Answer 15

Synth progest blocks FSH/LH Release for contraception, thickens cervical mucus

Question 16

Anastrozole and Exemestane are both ____ inhibitors

Answer 16

Aromatase

Question 17

Commy Clomiphene Use

Answer 17

Anovulation or amenorrhea (trying to get preg)

Question 18

The double ER-Blocker, Raloxifen 2 sFx

Answer 18

Hot Flashes, Leg cramps

Question 19

Name the 2 aromatase inhibitors used to treat ER Breast Cancer

Answer 19

1. Ana-Strozole

2. Exe-Mestane

Question 20

When Levonrgestrel is used as Morning-After, what route and amount of dose is taken?

Answer 20

• Oral

- 0.75

Question 21

Key difference of Levonorgestrel as Monring After vs Ulipristal morning after pill.

Answer 21

• Ulipristal is a single dose that BLOCKS endogenous progestrone
• Levo is a double dose that USES progesterone to thicken mucus and inhibit conception

Question 22

In regards to Women Pharm

Finasteride MOA

Answer 22

Inhib 5a-Reductase for less DHT production

Question 23

In regards to Women Pharm

Ulipristal MOA

Answer 23

Mixed progest recptor binder

Question 24

Ethinyl estradiol 4 Uses

Answer 24

Contraceptive, Ovarian cysts, endomet cancer, breast disease

Question 25

“Morning after” Ulipristal 3 sFx

Answer 25

Nausea, cramps, painful menstruation

Question 26

In regards to Women Pharm

Finasteride 3 Use

Answer 26

BPH, hirsutism, baldness

Question 27

Anastrozole and Exemestane (Aromatase blockers) 3 sFx less than Tamox, 2 sfX more than Tamox

Answer 27

Hot flash, Vag bleed, Endomet Cancer (less than Tamoxifen); Arthralgias, Vag Dryness (more than tamoxifen)

Question 28

The 5AD-Blocker, Finasteride 2 sFx

Answer 28

Less libido, Erectile Dysfxn

Question 29

The double ER-Blocker, Raloxifen 2 Uses

Answer 29

Osteoporosis, prevent breast cancer (SERM)

Question 30

“Commy” Clomiphene 3 sFx

Answer 30

Hot flashes, Multiple preg, Nausea

Question 31

Raloxifen 2 MOA, key distinguisher from Tamoxifen

Answer 31

Breast AND Endomet E2-R blocker, Bone E2-R Potent Agonist (SERM)

Question 32

The IRR aromatase-inhib Exemestane Use

Answer 32

ER Breast Cancer