Week 9 Topical - Corticosteroids Flashcards
Which of the topical corticosteroids is available without a prescription?
Hydrocortisone
The topical corticosteroids include: hydrocortisone, fluocinolone, triamcinolone, and clobetasol. Which is the most potent? The least?
High
Clobetasol
Fluocinolone
Triamcinolone
Hydrocortisone
Low
Cheesy Feet Tastes Heavenly
What is the MOA of the topical corticosteroids
- inhibit pro-inflammatory mediators
- decrease vacular dilation and permeability
- decrease epidermal cell proliferation
Absorption of the topical corticosteroids may be altered by:
- Use of occlusive dressings (increased)
- Skin temperature (warm = increased)
- Thickness of skin at site of application
What are some contraindications/cautions for topical corticosteroids?
- Pregnancy
- High dose/potency use on face, groin, axilla
- Current tinea infections
What are the possible ADR for topical corticosteroids?
- Skin irritation/dryness
- Maceration/atropy of skin
- Secondary infections
What are some indications for topical corticosteroids?
Inflammatory skin diseases
* dermatitis
* psoriasis
* eczema
There is a _______ probability for tolerance when using topical corticosteroids
high
True or false
Patients should be instructed that they can abruptly stop their topical corticosteroids
False - rebound reactions can occur
Therapy with high dose/potency topical corticosteroids shouldn’t last longer than ________
2 weeks
True or false
The finger tip unit (FTU) is useful when demonstrating topical corticosteroid dosing to patients
True
During use of topical corticosteroids __________ monitoring may be necessary with high doses/potency or in younger patients
adrenal funtion
