Week 12 - Drugs Used to Treat Addiction

Question 1

Naloxone MOA

Answer 1

works by binding to opioid receptors in the brain, blocking the effects of opioids and reversing their toxic and respiratory-depressant effects

Question 2

Naloxone indication

Answer 2

emergency situations to rapidly reverse the effects of opioid overdose and restore normal respiration.

Question 3

Naloxone SE

Answer 3

nausea, vomiting, headache, dizziness, or increased heart rate

Question 4

Buprenorphine MOA

Answer 4

a partial opioid receptor agonist and a weak opioid receptor antagonist. It binds to the opioid receptors in the brain, producing weaker opioid effects compared to full agonists like heroin or morphine

Question 5

Buprenorphine indication

Answer 5

used as a medication-assisted treatment (MAT) for opioid addiction. It helps reduce withdrawal symptoms and cravings, allowing individuals to taper off opioids more comfortably and effectively. Moderate pain.

Question 6

Buprenorphine SE

Answer 6

Same as other opioids

Question 7

Naltrexone MOA

Answer 7

opioid antagonist, which means it blocks the effects of opioids by binding to opioid receptors and preventing them from being activated.

Question 8

Naltrexone vs Naloxone

Answer 8

Naltrexone is longer acting. Naltrexone is used in the maintenance phase to prevent relapse. Naloxone is used in the acute phase of overdose.

Question 9

Naltrexone indication

Answer 9

used to treat both OPIOID and ALCOHOL addiction. For opioid addiction, it is used in the maintenance phase to prevent relapse. For alcohol addiction, it helps reduce alcohol cravings and discourage relapse.

Question 10

Naltrexone SE

Answer 10

nausea, headache, dizziness, fatigue, and gastrointestinal upset.

It is hepatotoxic, so regular monitoring is recommended.

Do not use in patients who are, or could use opioids.