Week 10 - Anxiolytics/Antidepressants

Question 1

Tricyclic antidepressants are less safe for high risk suicide patients because?

Answer 1

Overdosing can be easy and fatal.

Question 2

Tricyclic antidepressants are contraindicated in patients with?

Answer 2

Cardiac disorders

Question 3

Tricyclic antidepressants generally _____________ QT interval.

Answer 3

Prolong

Question 4

MOA of tricyclic antidepressants?

Answer 4

Inhibits reuptake of norepinephrine and 5-HT in presynaptic terminals. Increases availability to bind to postsynaptic terminals.

Blocks serotonin, alpha adrenergic, histaminic, and muscarininc receptors.

Question 5

Tricyclic antidepressants are indicated for?

Answer 5

Depression
Neuropathic pain (Amitriptyline)
Insomnia
Panic disorder
Bedwetting
(Imipramine)

Question 6

The development of __________ is of concern with benzodiazepines

Answer 6

Dependence

Question 7

Benzodiazepines are contraindicated in what populations?

Answer 7

Pregnancy
Lactation
Hepatic and renal patients
Narrow-angle glaucoma

Question 8

Benzodiazepines are frequently prescribed to treat?

Answer 8

Anxiety and insomnia

Question 9

What is the drug ending for most benzodiazepines?

Answer 9

-lam and -pam

Question 10

What is the mechanism of action of barbiturates?

Answer 10

Produce sedation and sleep through decreasing sensitivity to stimuli in reticular formation.

Question 11

Barbiturates combined with alcohol has contributed to?

Answer 11

Death. (;

Question 12

What is the drug ending for most TCAs?

Answer 12

-triptyline, -amine, -epin.

DANI
Doxepin, Amitriptyline, Nortriptyline, Imipramine