Week 6 - Hepatits Flashcards
what is hepatitis
- inflammation of the liver
what are some causes of hepatitis (7)
- viruses
- chemicals
- drugs
- alcohol
- autoimmune diseases
- metabolic disorders
- genetic abnormalities
what is the function of the liver (7)
- filter the blood coming from the digestive tract, before passing it to the rest of the body
- detoxifies chemicals and metabolizes drugs
- secretes bile that ends up back in the intestines
- makes proteins important for blood clotting and other functions.
- bile –> fat metabolism
- helps regulate BG by storing glucose
- ammonia –> urea
what are some symptoms of hepatitis during the acute phase (10)
- GI symptoms
- RUQ discomfort
- altered taste & smell
- nonspecific symptoms
- hepatomegaly
- lymphadenopathy
- splenomegaly
- hepatic jaundice (increased conj and unconj)
- darkened urine (d/t increased conj)
- light, clay colored stool (inflammation = swelling = conjugated bilirubin cant flow out of liver)
- pruritis
what are some GI symptoms present in hepatitis (6)
- anorexia
- NV
- CD
- altered taste & smell
what nonspecific symptoms are present in the acute phase of hepatitis (6)
- malaise
- fatigue
- headache
- low-grade fever
- arthralgia
- skin rashes
what symptoms are present in chronic hepatitis (2)
- no symptoms
- or non specific symptoms
what are some nonspecific symptoms present in chronic hepatitis (5)
- malaise
- easy fatigability
- mylagia
- arthralgia
- hepatomegaly
what are 2 possible complications of hepatitis
- fulminant hepatitis
- cirrhosis
what is fulminant hepatitis
- acute clinical syndrome that results in severe impairment or necrosis of liver cells and potential liver failure
what can be used to diagnose hepatitis (3)
- viral serological tests
- serum liver enzymes
- liver function tests
what are viral serological tests
- uses serological markers (viral antigens and antibodies) to diagnose viral hepatitis
what are serum liver enzymes useful for
- cannot differentiate between different types of hepatitia, but can determine the type of liver injury –> if due to liver cell injury or bile duct abnormality
what serum liver enzymes are assessed to diagnose hepatitis (4)
- AST
- ALT
- ALP
- GGT
what is assessed during liver function tests (4)
- serum albumin
- serum bilirubin
- prothrombin time
- INR