Week 4 - DVT Flashcards
what is DVT
- disorder involving a thrombus in a deep veing
what 2 veins does DVT typically effect
- femoral
- iliac
what are the 3 main factors in the cause of venous thrombosis
- venous stasis
- endothelial damage
- hyerpcoaguable blood
what are risk factors for venous stasis (7)
- obesity
- pregnancy
- HF
- afib
- long trips w/o regular exercise
- prolonged surgical procedure
- immobolity for long periods
what are causes of endothelial damage (7)
- surgery
- imtravascular catheterization
- trauma
- burns
- chemo
- DM
- sepsis
what can cause hypercoaguability of blood (4)
- sepsis
- oral contra
- smoking
- hematological disorders
what are symptoms of DVT (8)
- unilateral leg edema
- extremitity pain
- sense of fullness in thigh/calf
- paresthesias
- warm skin
- erythema
- fever
- positive Homen’s
what is a positive homen’s sign
- pain on forced dorsiflexion of the foot when the leg is raise
what are complications of DVT (4)
- PE (life threatening)
- chronic venous insufficiency
- phlegmasia cerula dolens
- venous leg ulcers
what are S&S of chronic venous insufficiency (5)
- persistent edema
- increased pigmentation
- secondary varicosities
- ulceration
- cyanosis of limb
when limb is placed in dependent position
what types of care are done for DVT (3)
- prevention and prophylaxis
- drug therapy
- surgical therapy
what are ways to prevent DVT in pts who are at risk (4)
- mobilization = easiest and most cost-effective method
- compression stocking
- sequential compression devices
- preventative anticoag
what are some ways to mobilize to prevent DVT (3)
- if on bed rest, turn q2h
- flex & extend feet, knees, hip q2-4 h
- ambulate 4-6 x/day as tolerates
what are sequential compression devices
- inflatable garments wrapped around the legs that apply intermittent external pressure
what meds are used routinely for prevention and treatment of DVT
- anticoags
what is the goal of anticoag therapy (4)
- prevent clot formation
- prevent propagation of clot
- prevent development of new thrombi
- prevent embolization
what are 4 major classes of anticoag therapy
- vitamin K antagonist
- direct thrombin inhibitor
- indirect thrombin inhibitor
- factor Xa inhibitor
anticoagulant therapy does not…
- dissolve the clot
what type of med is not recommended for DVT thromboprophylaxis
- aspirin
what is a type of vitamin K antag
- warfarin
how long does it take for warfarin to be effective
- 48-72 hr to affect PT time
- several days for maximum effort
due to the time it takes for warfarin to be effective, what is required
- overlap of a parental anticoag (ex. unfractioned heparin, low molecular weight heparin) for at least 5 days
- once warfarin at therapeutic lvl, d/c heparin
what blood coag test should be monitored w warfarin
INR