Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infectious Disease > Week 6: Antimicrobial resistance > Flashcards

Week 6: Antimicrobial resistance Flashcards

1
Q

Case 1

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Question

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Mechanisms of resistance

A
  • Intrinsic resistance
  • Transfer of genetic material encoding for resistance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is intrinsic resistance

A

Innate ability of bacterial species to resist activity of drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What mechanisms of resistance can be in Genetic material coding for resistance

4 listed

A
  • Alteration of target antibiotic
  • Enzymatic degradation of antibiotic
  • Changes in cell wall permeability
  • Production of efflux pumps
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Case 2

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Question

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mechanisms of horizontal gene transfer

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is Transformation?

A
  • Transformation involves uptake of short fragments of naked DNA by naturally transformable bacteria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is Transduction?

A

Transfuction involves transfer of DNA from one bacterium into another via bacteriophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is Conjugation?

A

Conjugation involves transfer of DNA material via sexual pilus and requires cell-to-cell contact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Case 3

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Question

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

VRE AKA

A

Vancomycin-Resistant Enterococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

VSE AKA

A

Vancomycin-Susceptible Enterococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe the mechanism of vancomycin susceptible enterococci

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Describe the mechanism of vancomycin-resistant enterococci

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Case 4

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the MIC

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Case 5

21
Q

Question

22
Q

Case 6

23
Q

Question

24
Q

Question

25
Q

Case 7

26
Q

Question

27
Q

Case 8

28
Q

Question

29
Q

Case 9

30
Q

Question

31
Q

Explain how drug resistance arises

32
Q

Why and when to order Genotype testing of HIV

33
Q

Question

34
Q

Causes of HIV resistance to ARVs

6 listed

35
Q

How to prevent HIV Resistance to ARVs

36
Q

Case 10

37
Q

Question

38
Q

Mycobacterial Resistance mechanisms

A
  • Naturally occurring mutations can confer resistance
  • On drug-therapy, drug-susceptible organisms are killed selecting for drug-resistant mutants
39
Q

When should Mycobacterial Resistance be considered in patients

A
  • Who remain culture positive after 2-4 months of treatment
  • Patients who have previously been treated for TB
  • Contacts of patients with drug-resistant TB
  • Patients born in countries or who reside in setting where drug-resistant TB is prevalent
40
Q

Treatment principles for Active TB

41
Q

Case 11

42
Q

Question

43
Q

Case 12

44
Q

Question

45
Q

Case 13

46
Q

Question

47
Q

Question

48
Q

Case 14

49
Q

Question

Infectious Disease (82 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions