Week 3 - Mon - Trafficking of Membrane Proteins Flashcards

1
Q

vesicles

A

membrane enclosed sacks

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2
Q

membrane enclosed sacks

A

vesicles

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3
Q

ER

A

endoplasmic reticulum

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4
Q

ribosomes attach to a part of the cell membrane called the ________________

A

rough endoplasmic reticulum

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5
Q

the smooth endoplasmic reticulum lacks_________

A

ribosomes

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6
Q

cytosol

A

contains many metabolic pathways , protein synthesis, the cytoskeleton

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7
Q

nucleus

A

contains main genome, DNA + RNA synthesis

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8
Q

ER (endoplasmic reticulum)

A

synthesis of most lipids, synthesis of proteins for distribution to many organelles and to the plasma membrane

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9
Q

golgi apparatus

A

modification, sorting, and packaging f proteins and lipis for either secretion of delivery to another organelle

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10
Q

lysosomes

A

intracellular degradation

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11
Q

endosomes

A

sorting of endocytosed material

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12
Q

mitochondria

A

ATP synthesis by oxidative phosphorylation

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13
Q

chloroplasts

A

ATP synthesis and carbon fixation by photosynthesis

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14
Q

peroxisomes

A

oxidation of toxic molecules

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15
Q

how are organelles held in place?

A

attachment to cytoskeleton / microtubules

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16
Q

how do mitochondria, chloroplasts, peroxisomes and the nucleus get their required proteins?

A

directly through the cytoplasm

17
Q

how do the lysosomes, endosomes, golgi apparatus, and inner nuclear membrane get their proteins?

A

indirectly through the ER –» golgi –»distributed

18
Q

the synthesis of virtually all proteins begins on ______ in the ______

A

ribosomes, cytosol

19
Q

a sorting signal is______

A

an amino acid sequences that directs the protein to the organelle in which it is required

20
Q

3 methods of protein transport

A

nuclear pore, protein translocators, transport vesicles

21
Q

proteins must _______ to work through the _______ and move from the cytosol into the ER

A

unfold , protein translocator

22
Q

the signal sequence is typically between ___ and ____ amino acids long, and is usually______ from the protein once finished

A

15-60, removed

23
Q

_______ encloses the nuclear DNA and defines the nuclear compartment

A

nuclear envelope