Week 3 - Lecture - Cytoskeleton etc.

Question 1

cyto

Answer 1

of cell or cells

Question 2

transcytosis

Answer 2

moving through/across cell

Question 3

endo

Answer 3

within

Question 4

exo

Answer 4

outside

Question 5

-some

Answer 5

body

Question 6

endosome

Answer 6

within body / body within

Question 7

ligand

Answer 7

binding molecule

Question 8

cytosis

Answer 8

movement of molecules (in, out, through cells)

Question 9

endocytosis

Answer 9

movement into a cell

Question 10

exocytosis

Answer 10

movement out of a cell

Question 11

lumen

Answer 11

inside space of a tubular structure

Question 12

epithelial

Answer 12

thin, lining of cavities and sufaces

Question 13

visicle

Answer 13

a small fluid-filled bladder, sac, cyst, or vacuole within the body. Used for transcytosis

Question 14

3 types of cytoskeletal filament systems in eukaryotic cells

Answer 14

intermediate filaments, microtubules, actin filaments

Question 15

examples of intermediate filaments in your body

Answer 15

hair, fingernails

Question 16

intermediate filament proteins ______ into _______

Answer 16

assemble , large fibers

Question 17

are intermediate filaments always polar?

Answer 17

no, there is no inherent polarity

Question 18

structural sub-components of intermediate filaments

Answer 18

monomer, dimer, tetramer

Question 19

at what point does a filament lose polarity?

Answer 19

tetramer

Question 20

does an actin filament have a polarity?

Answer 20

yes

Question 21

how is actin assembled?

Answer 21

a collection of hydrophobic interactions between identical subunits (polar)

Question 22

G-actin

Answer 22

un assembled subunits of actin. Actin monomers

Question 23

F-Actin

Answer 23

microfilaments of assembled actin

Question 24

when _____ actin subunits come together, the stabilize each other and serve as a nucleus for actin fibers

Answer 24

3

Question 25

actin nucleation is ______ and ______, while elongation is _______ and _________

Answer 25

hard, slow —> easy, fast

Question 26

_______ ___________ of an actin filament meshwork just under the cell surface can drive forward movement of the cell cortex

Answer 26

explosive polymerization

Question 27

ARP

Answer 27

actin related protein

Question 28

a ______ motor converts chemical energy from ATP into mechanical movement

Answer 28

myosin

Question 29

without ATP, myosin is ______ to the actin

Answer 29

bound

Question 30

ATP / Myosin truck analogy

Answer 30

air brakes

Question 31

____ _______ leave kinks and ‘cut’ the actin filaments

Answer 31

severing proteins

Question 32

_____ _______ link vesicles and microtubules, and move the vesicles across the cell

Answer 32

motor proteins