Week 2- hormonal responses to exercise Flashcards

1
Q

How is plasma glucose levels maintained during exercise?

A
  1. mobilisation of glucose from liver glycogen stores
  2. mobilisation of FFA from adipose tissue, spares blood glucose
  3. Gluconeogenesis from amino acids, lactic acid and glycerol
  4. blocking entry of glucose into the cells
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2
Q

How do slow-acting hormones act?

A

in a permissive manner to allow other hormones to exert their full force

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3
Q

What is the role of the thyroid hormone?

A

Influence the number of receptors on the surface of the cell for other hormones to react with

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4
Q

What does Triiodothyronine enhance?

A

effect of epinephrine to mobilise free fatty acids from adipose tissue (T3)

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5
Q

What is the role of growth hormones?

A

-essential for growth of all tissues
-increases amino acid uptake and protein synthesis
-spares plasma glucose
-mobilises fatty acids from adipose tissue

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6
Q

What changes to plasma GH when exercise intensity increases?

A

Plasma growth hormone increases

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7
Q

What is cortisol?

A

Steroid hormone derived from cholesterol and secreted from the adrenal cortex
-contributes to the maintenance of plasma glucose

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8
Q

What is cortisol stimulated by?

A

-stress via adrenocorticotrophic hormone (ACTH)
-exercise

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9
Q

What is diurnal variation?

A

concentrations peak on the morning and drop throughout the day

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10
Q

What are the effects of cortisol mediated by?

A

DNA transcription and translocation to protein synthesis

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11
Q

Where are catecholamines secreted from?

A

adrenal medulla

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12
Q

What kind of hormone is epinephrine and norepinephrine?

A

Fast acting hormones part of the fight or flight response

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13
Q

What increases epinephrine and norepinephrine?

A

-exercise
-increased BP and HR during exercise

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14
Q

What causes a rapid decrease in catecholamines?

A

endurance training

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15
Q

What causes more rapid glycogen depletion?

A

high intensity exercise

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16
Q

What is the role of plasma epinephrine?

A

stimulate glycogenolysis via b1 receptor

17
Q

Where does the pancreas secrete counter-regulatory hormones from?

A

islets of Langerhans

18
Q

What is the role of insulin when released from b cells?

A

promote the storage of glucose and amino acids and fats

19
Q

What is the role of glucagon when released from a cells?

A

promote the mobilisation of fatty acids and glucose, stimulates gluconeogenesis in the liver

20
Q

How much does insulin concentration drop during moderate intensity exercise?

A

~50%, favouring the metabolism of glucose from the liver and FFA from adipose tissue

21
Q

What is the primary stimulus for the secretion of insulin and glucagon?

A

Plasma glucose

22
Q

What do hormones that are elevated during exercise favour?

A

Mobilisation of fat

23
Q

Why does FFA oxidation decrease during heavy exercise?

A
  1. high levels of lactic acid
  2. increase hydrogen concentration inhibits HSL
    3.inadequate blood flow to adipose tissue
  3. insufficient albumin to transport FFA in plasma
24
Q
A