Week 12 Flashcards

0
Q

Psychosomatic disorders, see list. Q

A

Arguably opal almost any disorder seems to have psychosomatic roots. But why a specific type of disorder vs others.

  1. Genetics!
    Salt rats eg. Predisposed to develop certain problems.
  2. For physical disorders, experiences play a role.
  3. Learning expectancy
    Pms

Conditioning, leads to learned physical responses. Particulary to stress. Guinea pig and cow serum. Pavlovian condition to smell of serum,

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1
Q

PsychosomTic, stress, Alfred ex.

Mind and body inseparable

A

Archer kid, deep brain stem tumor. Right hand less strength.
Family problems.
Hamilton fought kids battles
School, dog, medicine man boy spirit.

Emotionality and stress can impact an individual.

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2
Q

Stomach ulcers

A

Long history, Pavlov, Beaumont wolf.
Bullet stomach examples.
Secretions correlate with emotion. Overcompensation of the parasympathetic Ns. Overshoots, found ulcers develop.
So fine as long as stress get sick once relax, need to be extremely careful.

Antacid, note, they are useless. Relapse high.

Helicobacter pylori.
80% effective treatment.

BUT STRESS DOES STILL MATTER
3/4 have that bacteria. Not presence alone leads to some do not respond to mess, not all with stomach ulcers. Have h pylori.

Complex equation,
Examples.
Mouse study
Bacteria in gut effects mood.
Explore, happily, less stress or anxious.
Cut vagus nerve get worse.
Know bacteria plays a role! Eat yoghurt.

Ulcer production in monkey.
Shock seems to me to show chronic stress is the issue!
Circadian rhythm idea. Failure to replicate with other animals.
Contradicts Control idea. Feelings of self efficacy.

Women swallow 3 tubes.
Ph, baking soda, water
Measure acidity of stomach, see ph. Money used they could control.

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3
Q

Personality patterns and different ulcers!

A

Uc compliant

Pu resistant.

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4
Q

Heart disease. Clogged pip problem.

A

Not that simple though,

Facilitating build up is the issue. Not really the clean up that drugs take care of.

Chd medicine good at treating not at preventing.
Cholesterol 2% effectiveness! aspirin 1%. Incredible.
Standards for lipids set by drug companies!

All those risk factors common think only account for 25% of chd.
Hypertension and high LDL.

To tsss monkeys put them in foreign situations.
Looking at stress and heart disease. Dominance hierarchies.
Thickening of arteries. So vertical cultures have higher chd. Or job strain. Demanding jobs with little control. Require autonomy support! Study supports.
H attack survivor study. Had less oxygen to heart during stressor.

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5
Q

Coronary prone behaviour prone pattern of

A

Competitive achievement, hyper
TYPE A! Sisafus likely to develop heart attack.

Type b are laid back. Less likely for heart attack. Rela to holesterol.

Study confirms. Esp. For

So type be with ok cholesterol. Doesn’t matter if they smoke or weigh a lot.

But really. Type a only reflects 1%
Pissed off personality. This specific aspect more moderately predicts! Phew.

Culture is most important.
Bangor and roseto
Pennsylvania towns.
Italian village. Vs typical American. (Wrong order but you can get)
Roseto collectivistic society, less chd.

Diet doesn’t matter, living western culture kills!
Interesting argument. But diet does play a role! Just less than what we think.

S

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6
Q

Endodomic pleasure. Well being model see diagram.

High ell being less heart disease.

A

But dean ornish, lifestyle change, change genes. .
Prostate, heart disease. Low fat, ugh.
Most adhered changed almost 40% likely due to reduced stress.

Depressed ppl really screw up their bodies! Poor studnets I think
Depression leads to inflammation, increases chd and depression. Overuse of immune system. Build up plaque.

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7
Q

Psychoneuralimmunology wow.

A

See diagram! Wow.
Immune system not a closed system.

Emotions affect CNS and hormones and immune system and disease,

Going through this quickly. Immune system
Antigen, lymphocytes helper T cell.

Family harshness of kids families.

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8
Q

Stress and immunity

3 mile island. Nuclear bomb stressor

A

More drugs and issue,s
Impairments in endocrine system.

Also study looking at mono in military
2/3 had.

Colds, too

Stress and cancer.
Stress does not cause cancer, but related to development, progression and prognosis!

See the 5 reasons on slide!
Depression finally. Reduced white cells and killer cells.

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9
Q

Dsm 5 vs 4 somatotropin disorders

A

Somatotropin, no apparent physiologic disorders.
So usually due to stress.
First appeared in dsm 3

5 eliminate overlap distinguished in 5
Somatic symptoms disorders.

Distinction medically explained dualism, gone.

Issues, restrictions are a mistake. Anxiety is order overlap. Broad catageory better. Hard to differentiate medical cognition present. Overlap still an issue.

All collapsed into one.

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10
Q

Motheres depressive symptoms. Negative reactivity regulation of emotion.

A

Reactions: negative - suppress
Or unresponsive,

Low aversive, less neg.
More aversive, increase negative affect.
More neg, more mom depression, more neg.

Measure, completed cesd” initiantes discussion interaction.

3 models. Mom dep, child, reactions.
3 interaction.

All confirmed.

But mom child adversity did not predict something.

Faster increase in negative, except in model 3.

Low aversive and reactivity, in child, increased mdd, less negativitivty. Therefore suppressed her neg. Behaviour.

Low effort response preference.
Suggests threshold, leads to grater punishment. Of course it is a vicious circle.

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11
Q

Epi genetics.

A

No modification of DNA.

Development and inheritance.

Nucleoside spacing.g
Acetylation or methylation.

Mice and social defeat.
Rats early life maternal grooming.
Less grooming more anx. Less glucocorticoid receptors.

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12
Q

can condition nueropsycho immunology.

Enhance killer cell study. Oder saccharine and drugs. Immune system is succeptibility to

A

LeaRning!

So past history also influences immune system
Interleukin 6. Difficult family history means you die sooner.

See another diagram.

Social genetic and physical impact symptoms, determines disease and health are.

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13
Q

Anxiety look at it in to ways

A

Theoretically. ?
Respons

Tests do not correlate with other measures of anxiety.
Case of Sue. Anticipation leads to anxiety.

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14
Q

Theory of anx, anticipation is critical

Like in

A

Psychianalytic theory. I’d gets squeezed.
Relationship involved, reservoir of anx. Parent treatment leads outcomes. Or anticipated loss of rela.
Behavioural view.
Variable reinforcement then shock, then stops.
Anxiety is disruption of ongoing behaviour! Still anticipation of negative stim. Hmm interesting.

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15
Q

Espouses to anxiety.

Reservoir of action potential.

A

Vigilant, overaactice, excited.
Behaviour ineffective.
Over generalize, response rigidity.
This seems like the norm for some ppl though to me…. Question as abnormal psych imo

Arousal and disorganization.
Christka exam, press a bulb, in a right hand. Word association test. Couldn’t do it in a rhythmic fashion, longer than controls. Profound effect of arousal on perforamnce.

Yorkers Dodson lay. Optimal level of arousL. Curve. Inverted u.
In spite of what you know, optimal level. To little or mcu stress highly detrimental.

16
Q

Source of anx. .

A

Evo. Spent most time survival based.
Cortex, Limbic, sensory, thalamus amygdala diagram. Hippocampus. (Releases GABA,inhibit amygdala.) recognize harmless. Hmm.
Hypothalamus,
Sympathetic nervous system.

Cortex can modify whole reaction. Breathe and think. ,

Brain imagery eg. Amygdala responses.

Eyes and mouth key to fearful face.

Anxiety fibre tracts to frontal loves not as strong. Ability to control is even less, due to less white matter, asg amygdala. Show for high anx ppl.

Serotonin genotype may predict this. CC genotype, more likely to show right amygdala activity. Correlates with trait anxiety.
Not while story!
Social anx, different area light up.

Subgenual anterior cingulate for depression.

17
Q

GAD

A

Three features
Uncontrolled ability of worry
Intolerence of uncertainty and
Ineffective problem solving.

2-3x female to male. Lifetime 5%

Dsm,
Need to show over 6 months. Very important. Otherwise all of us woul have this. Half the time.
Controlling worry hard, irritability. Sleep disturbance.
Not due to other things as listed on slides.

Information processing attention all bias maintaing worry.

Event - over emphasis on vigilance, attention to threat generalized.
Inability to disentangle focus, anxiety, no control of info on stim. Self perpetuating.

SOURCES
Serotonin genes,
Early experiences. Gender difference study.
Sons autonomy supporting. Girls, controlling. Leads to dependency.

18
Q

What comes first anx or depression.

Most think anx, but data shows

A

Actually cannot really seperate the two. Highly related.

19
Q

On to panic disorder.

A

Re likely of women, of hold bearing age.

Panic word origin, from greek god of fertility. Pan frightens strangers.

Panic attack need 4 symptoms, have so many symptoms.
Disorders occur frequently over time and affect behaviors.

Prevalence, 1%
More prevalent in women, but, in university pop. Prevalence 5%
Comorbid with depression, and geographic.

20
Q

Panic attack induction study.

A

Hyperventilation,
Co2

Lactate sodium
Caffeine
Progesterone
Stressors

Model I not important to know for exam, he doss not agree with it.

Panic attacks basic results from misinterpretation.
,

Bio-panic test

Fast breathing test.

Panic ppl vs normals.

Breathing every second.
Only in bio panic, interpreted physiologic responses to mean, did they have a panic attack. For panic patients.

May still have biological succeptibility.
Reduced GABA binding. Throughout the brain. Difference large. Anxiety dampening neurotransmitter.

Lack ability to dampen arousal, and are in fact more aroused!

21
Q

Meta analysis of panic disorder treatment.

A

Exposure best at treating symptoms.

Convincing person, situation will not produce panic attack, and if it does, cognitive reinterpretation.