Ab Week 7 Flashcards
Animal studies
methodology,
Anote knock outs.
Focus Selective breaking, !
Ex. Robert 1940, breed intelligence
Maze, breed best/poor assured isolated gene pools,
But, reLly you are manipulating, emotionality, not sure.
Another study flips results in water.
Imp. Cannot be sure what something is being measured.
Consequences not controlled for.
Silver foxes, (PLEINTROPY), lots of changes morphology due to domestication
INTERACTIONS are therefore imp to consider., bar harbor, ex. More and least aggressive strain, both right, handling different. –>different behaviour. Interactions imp. In ab PSYC.
Salt sensitive diet rats, die
Conflict stress, high blood pressure died, even with no salt.
**Suggests vulnerable for one thing, leads to interaction. Whereby vulnerable to another thing. **
Human ex. Children with violent non violent parent, interaction–> criminal history
Norma, McCory, a orton lawsuit,
Freekonomonoics, ab orton —> less criminal! due less kids unstable famili.
Gene x behavioural or drug interactions
Affects all stage of development.
Mao acticity likelihood antisocial behaviour, orchids dandelions idea note. S or. L genotype, mdd (more ss) interaction
Cont gene, can ibus –> scz
What is fragile X
most frequent form of inherited disorder, does not follow strict Mendelian rules, many carriers w/o symptoms, symptoms vary from mild to extreme (learning disabilities to mental disabilities like retardation)
Leading inherited cause of autism, physical abnormalities
Abnormal arms of chromosome.
MAL ESmore at risk than females, because males only have one copy of X chromosome,
In subsequent generation more likely to appear, in future gen, and more severe. -This is Called ANTICIPATION
More than 55 copies, means likely to have the abnormality,
Effects neural dev, accounts physical and mental varia.
Differ in brain GREY and WHITE matter
Interactions and TYPOLOGY
Interactions mentioned in previous card.
Typology,
Ex. Of I,balance of humors,
Carl young intro extro.
SHELDON
Body type reflectin of ones genes, controlled behaviour
Endomorphic, ec tomographic, mesomorphic,
Fat, skinny big nerves, muscular
Viscer, cerebretivr, somatotonic
Found high r between two.
This all shows a lot of self fulfilling prophecy, what we look like controls enviro Nd controls us. That’s what it means. And that’s also what genes do.
Children study,
Reactors are ones at risk of disorders,
Non reactors, lead to other disorders. Anti social
Twin pairs, genic effect
Reasons for studying biochemistry in abnormal beha.
Imp. If agree genetics are imp, must know biochemistry.
Functional genetics,
Chemical anatomy of the brain
Neurotransmitters, neuro modulators, location I of activity.
Pharmacotherapy.
Carrier type of 21 p syndrome for Down syndrome
I’m
Synapse, synthesis
Stored, broken, taken up, 5 part step to function of synapses.
Glutamine in scz
It is higher, as is glutamine to glutamate ratio.
Choline too.
Shows drugs may not help the over release of glutamate. Leads to more glutamine to metabolize glutamate.
