Waterhouse- Friderichsen Syndrome

Question 1

Identify the bacterium that most commonly causes Waterhouse-Friderichsen syndrome.

Answer 1

Neisseria meningitidis septicemia

Question 2

State the treatment used for close contacts of someone infected with N. meningitids.

Answer 2

Rifampin

Question 3

Recognize the most common means of transmission for N. meningitidis.

Answer 3

By inhalation

Question 4

Name the main patient population infected by Waterhouse-Friderichsen syndrome.

Answer 4

Children are mainly infected, (Campers, college kids)

Question 5

Waterhouse-Friderichsen syndrome is characterized by massive ______

Answer 5

bilateral adrenal hemorrhage.

Question 6

Normally found in Children with E.coli serotyped O157:H7 adn characterized by hemolytic anemia, renal failure, and thrombocytopenia.

Answer 6

HUS- hemolytic uremic syndrome

Question 7

Laboratory Findings for HUS:
RBC
Hemoglobin & Hematocrit
Platelets

Answer 7

All decreased + schistocytes, proteinuria, and hematuria

Question 8

How to differentiate DIC from HUS?

Answer 8

DIC causes increased PT and APTT times whereas HUS has normal PT and APTT times